{"id":"W2261983366","doi":"10.1038/icb.2015.91","title":"Calcineurin B stimulates cytokine production through a CD14‐independent Toll‐like receptor 4 pathway","year":2015,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Calcineurin; Receptor; Cytokine; CD14; Toll-like receptor; Chemistry; Cell biology; Immunology; Biology; Medicine; Innate immune system; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001309212,0.0003360682,0.0001398198,0.000182053,0.0001339015,0.0002154725,0.000132469,0.0001717143,0.001126224],"category_scores_gemma":[0.0001295204,0.00008495795,0.0002263107,0.00009733031,0.0002014105,0.0001416695,0.0002174074,0.0003748249,0.0001909331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000263284,"about_ca_system_score_gemma":0.0002801004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006872254,"about_ca_topic_score_gemma":0.0009285711,"domain_scores_codex":[0.9998858,0.00002604634,0.000007997227,0.00001585139,0.00003687759,0.0000274314],"domain_scores_gemma":[0.9999233,0.00001285968,0.00002116047,0.000009083758,0.00001095543,0.00002255257],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001403028,0.00002876237,0.0001345889,0.00003722519,0.000003421202,0.00005251345,0.000006910288,0.00003081227,0.9987338,0.00006128925,0.00002395178,0.0007463452],"study_design_scores_gemma":[0.00009585451,0.0003828225,0.008238257,0.00001040315,0.000015923,0.0003178602,0.00002643015,0.001395427,0.9866093,0.0001003474,0.002802297,0.000005127521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912313,0.003431497,0.002487826,0.0001602336,0.00005428401,0.00004415229,0.0001561749,0.00005847204,0.002376075],"genre_scores_gemma":[0.9948556,0.001279065,0.001606685,0.00005215531,0.00002165146,0.00003525567,0.0001923484,0.000007765943,0.001949393],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001126224,"threshold_uncertainty_score":0.00376761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01840099730979499,"score_gpt":0.2438123835237453,"score_spread":0.2254113862139503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}