{"id":"W2261983366","doi":"10.1038/icb.2015.91","title":"Calcineurin B stimulates cytokine production through a CD14‐independent Toll‐like receptor 4 pathway","year":2015,"lang":"en","type":"article","venue":"Immunology and Cell Biology","topic":"NF-κB Signaling Pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; National Natural Science Foundation of China","keywords":"Calcineurin; Receptor; Cytokine; CD14; Toll-like receptor; Chemistry; Cell biology; Immunology; Biology; Medicine; Innate immune system; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003045782,0.0002712753,0.0002895986,0.00005664736,0.0001162636,0.0000116267,0.0002182624,0.0005658084,0.00003984394],"category_scores_gemma":[0.0001235934,0.00024091,0.00006752422,0.00008310058,0.0003561439,0.00000812173,0.0002401028,0.0002534196,0.00008095695],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002457944,"about_ca_system_score_gemma":0.0001187784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006715638,"about_ca_topic_score_gemma":0.00002717035,"domain_scores_codex":[0.9982492,0.000254187,0.0003011375,0.0007021384,0.00006475063,0.0004285961],"domain_scores_gemma":[0.9991668,0.00002317536,0.0001335083,0.0004603965,0.0001347262,0.00008141396],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004529167,0.0001238192,0.002014055,0.00001094318,0.0000803163,0.000008046125,0.0001816994,0.00005005129,0.9942653,0.0002072343,0.001294918,0.001310724],"study_design_scores_gemma":[0.001202057,0.001302067,0.0002794868,0.000006554533,0.00001905874,0.0001106629,0.0001569044,0.000008073602,0.8367721,0.0005672795,0.1593091,0.0002666661],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890663,0.007033885,0.0004212504,0.0003872273,0.001510102,0.0002607462,0.0000359595,0.00005236257,0.001232191],"genre_scores_gemma":[0.9958311,0.0005796754,0.0006432253,0.0003254123,0.0003687149,0.00004157515,0.0003490014,0.00002957922,0.001831709],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1580141,"threshold_uncertainty_score":0.9824024,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01840099730979499,"score_gpt":0.2438123835237453,"score_spread":0.2254113862139503,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}