{"id":"W2262527057","doi":"10.1096/fasebj.22.1_supplement.174.5","title":"Regulation of valvular interstitial cell phenotype by matrix mechanics involves alpha‐smooth muscle actin","year":2008,"lang":"en","type":"article","venue":"The FASEB Journal","topic":"Cardiac Valve Diseases and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Extracellular matrix; Cell biology; Interstitial cell; Actin; Calcification; Matrix (chemical analysis); Chemistry; Pathology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001314273,0.0002005428,0.00008820757,0.0001229704,0.0001466754,0.0003209047,0.00009290916,0.0001753673,0.0009809966],"category_scores_gemma":[0.0002051215,0.0001003306,0.0000860205,0.0000610351,0.0002098651,0.0001415967,0.000136517,0.0001810253,0.0001729966],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001393466,"about_ca_system_score_gemma":0.0001127425,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001992065,"about_ca_topic_score_gemma":0.0003308317,"domain_scores_codex":[0.9999015,0.00001727125,0.000007209774,0.00001905526,0.00003214851,0.00002284785],"domain_scores_gemma":[0.9998358,0.00004297353,0.00004098241,0.00001448118,0.0000315127,0.00003415214],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003790221,0.00001120061,0.00126665,0.00001332724,0.000002135818,0.00002894267,0.00001264508,0.00002281256,0.9970241,0.00005534602,0.0000157563,0.001509132],"study_design_scores_gemma":[0.0000320429,0.0005602049,0.1149563,0.00002045829,0.00002982773,0.0006348637,0.0001549735,0.003423571,0.8774956,0.0002979774,0.002387519,0.000006683223],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9958088,0.0007725182,0.001986544,0.00004643225,0.00001148246,0.000007823272,0.00003551525,0.00001964592,0.001311125],"genre_scores_gemma":[0.9979036,0.0004349816,0.0008914801,0.0000139388,0.000007660065,0.000006980491,0.00004461317,0.00000269999,0.0006941841],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009809966,"threshold_uncertainty_score":0.003281772,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01485109470016896,"score_gpt":0.2839868261327595,"score_spread":0.2691357314325906,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}