{"id":"W2262649635","doi":"10.1016/j.ccell.2016.01.010","title":"Bringing IDH into the Fold","year":2016,"lang":"en","type":"letter","venue":"Cancer Cell","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Enhancer; PDGFRA; Biology; IDH2; DNA methylation; Methylation; Mutant; CTCF; IDH1; Cancer research; Glioma; Molecular biology; Gene; Genetics; Transcription factor; Gene expression; Stromal cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00004555402,0.0002164778,0.0002786909,0.00003661126,0.00006878117,0.00002307116,0.0001317734,0.0002251953,0.001420269],"category_scores_gemma":[0.000004885088,0.0001081953,0.0001754842,0.00005118862,0.0000433049,0.00002255919,0.00004857435,0.0003700384,0.000281225],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003981316,"about_ca_system_score_gemma":0.0001034575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001036522,"about_ca_topic_score_gemma":0.00006278294,"domain_scores_codex":[0.9990083,0.00001802561,0.0001417489,0.0002995975,0.0002257826,0.0003065476],"domain_scores_gemma":[0.9992366,0.00008986941,0.00008661084,0.0004917381,0.00004458173,0.00005058216],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000004817266,0.00001412629,0.0008114472,0.0001438673,0.0001081654,0.0004991958,0.0001662498,2.678922e-7,0.000310326,0.000004183634,0.9852544,0.01268294],"study_design_scores_gemma":[0.0007110857,0.000037176,0.0002066825,0.0004491055,0.0003182367,0.000009846638,0.00001152857,0.000002765101,0.006354828,0.00003841194,0.9917293,0.0001311012],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002856522,0.02453608,0.00000873086,0.937601,0.001057904,0.0004192658,0.0000198345,0.00004907549,0.0334516],"genre_scores_gemma":[0.02229413,0.003756566,0.00006384863,0.9313468,0.01295669,0.0004546204,0.00005444729,0.00009692068,0.02897596],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02077952,"threshold_uncertainty_score":0.9994926,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01504877179218443,"score_gpt":0.2650238936997439,"score_spread":0.2499751219075595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}