{"id":"W2262759738","doi":"10.1371/journal.ppat.1005427","title":"Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; RNA; Polymerase; Molecular biology; Influenza A virus; RNA polymerase; Cell biology; RNA polymerase III; Virus; Virology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002604305,0.0003345453,0.0005822877,0.0002638961,0.0002577753,0.00001296575,0.0001724366,0.0001653267,0.000166102],"category_scores_gemma":[0.0009480111,0.0002312677,0.0001802322,0.0004994823,0.0002984015,0.0002335486,0.00008980882,0.0002587396,0.00008419669],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000228591,"about_ca_system_score_gemma":0.0002731148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002220185,"about_ca_topic_score_gemma":0.00005152781,"domain_scores_codex":[0.9972839,0.000163349,0.0005460185,0.0004972452,0.0008560425,0.0006534357],"domain_scores_gemma":[0.9983918,0.0001249375,0.0001859892,0.0004714956,0.0005650916,0.0002606765],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0009190617,0.0007043746,0.005307344,0.0001645705,0.0003808296,0.00003210515,0.001099807,7.097468e-8,0.9862703,0.00007505743,0.0008940532,0.004152409],"study_design_scores_gemma":[0.00305529,0.001277904,0.01183943,0.0004737687,0.0001525086,0.000005344612,0.0001212614,0.00001310592,0.9790813,0.00002147202,0.003687955,0.0002706144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992694,0.001793615,0.0001634651,0.0009222674,0.00003686289,0.001727006,0.001280679,0.0001210396,0.001261038],"genre_scores_gemma":[0.9964572,0.0002003224,0.0004018405,0.0006084128,0.0001076748,0.0003717254,0.00002016104,0.000069755,0.00176287],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.007188974,"threshold_uncertainty_score":0.9430822,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05278446634615175,"score_gpt":0.3116961381703411,"score_spread":0.2589116718241894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}