{"id":"W2262759738","doi":"10.1371/journal.ppat.1005427","title":"Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein","year":2016,"lang":"en","type":"article","venue":"PLoS Pathogens","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research","keywords":"Biology; RNA; Polymerase; Molecular biology; Influenza A virus; RNA polymerase; Cell biology; RNA polymerase III; Virus; Virology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001539088,0.000434236,0.0002399558,0.000130682,0.0001250033,0.0004126173,0.0001327415,0.0001963206,0.0004940225],"category_scores_gemma":[0.0001416502,0.0001927296,0.0003332855,0.00007530384,0.0001644963,0.0001994273,0.0001897038,0.0003788587,0.0003498328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002173557,"about_ca_system_score_gemma":0.0001587253,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000317606,"about_ca_topic_score_gemma":0.0003611892,"domain_scores_codex":[0.999871,0.00002355481,0.00001490614,0.00003707632,0.00002706004,0.00002640726],"domain_scores_gemma":[0.9998637,0.00003701701,0.00004143448,0.00001661282,0.00001730732,0.00002385052],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003562951,0.000005794323,0.0001176589,0.000009556522,0.000002612261,0.00001677172,0.000004112267,0.00001578535,0.9994861,0.00002198854,0.000006307813,0.0002776837],"study_design_scores_gemma":[0.000004489203,0.0001561101,0.00353404,0.000002601657,0.000006144029,0.0002251255,0.0000109352,0.001063443,0.9943415,0.00002390444,0.0006292737,0.000002425756],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.992326,0.002139812,0.004587925,0.00003433038,0.0000173455,0.00001647067,0.0001638001,0.00006862505,0.0006456482],"genre_scores_gemma":[0.9938437,0.0008672711,0.00300601,0.00003994533,0.000009740776,0.00002836335,0.0006873673,0.0000308405,0.001486895],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004940225,"threshold_uncertainty_score":0.001652718,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05278446634615175,"score_gpt":0.3116961381703411,"score_spread":0.2589116718241894,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}