{"id":"W2262977121","doi":"10.20381/ruor-4358","title":"Repurposing 13-Cis-Retinoic Acid: A Potential Treatment for Aneurysms-Osteoarthritis Syndrome","year":2015,"lang":"en","type":"dissertation","venue":"","topic":"Retinoids in leukemia and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Canadian Institutes of Health Research; Genome Canada","keywords":"Repurposing; Retinoic acid; Osteoarthritis; Medicine; Internal medicine; Pharmacology; Bioinformatics; Chemistry; Alternative medicine; Biology; Pathology; Biochemistry; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000146887,0.0002573424,0.0002224144,0.0004447035,0.0002087362,0.0002317414,0.0001858471,0.0003814881,0.003672774],"category_scores_gemma":[0.00008459812,0.00009031923,0.0003712407,0.0002024556,0.0001958268,0.00012259,0.0001758674,0.0006251414,0.0009606392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002705545,"about_ca_system_score_gemma":0.000394727,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007155798,"about_ca_topic_score_gemma":0.003010507,"domain_scores_codex":[0.9999502,0.000008644503,0.000004956471,0.000007961496,0.00001473787,0.00001344239],"domain_scores_gemma":[0.9999713,0.000004553631,0.000007371492,0.000002141253,0.00000568393,0.000008966337],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001423462,0.0006370851,0.002286321,0.001408746,0.0001063426,0.002174717,0.000228373,0.000443571,0.6185099,0.004374517,0.007253999,0.3611529],"study_design_scores_gemma":[0.0009488263,0.004660505,0.01950472,0.0006665959,0.0004070768,0.01177371,0.0004714677,0.0005376777,0.557308,0.002348917,0.4013193,0.00005320131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.4263175,0.5014733,0.01043307,0.009071246,0.0008215216,0.0004596016,0.00142983,0.000467764,0.04952621],"genre_scores_gemma":[0.6635904,0.2828952,0.01126998,0.001801474,0.0002872605,0.0001917534,0.001244348,0.00003672705,0.03868286],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.003672774,"threshold_uncertainty_score":0.01228666,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01094879201837965,"score_gpt":0.2723538299957217,"score_spread":0.261405037977342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}