{"id":"W2262977137","doi":"10.1007/s00441-015-2277-6","title":"Connexin 43 promotes ossification of the posterior longitudinal ligament through activation of the ERK1/2 and p38 MAPK pathways","year":2015,"lang":"en","type":"article","venue":"Cell and Tissue Research","topic":"Connexins and lens biology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hôpital du Sacré-Cœur de Montréal; Université de Montréal","funders":"","keywords":"Cell biology; p38 mitogen-activated protein kinases; MAPK/ERK pathway; Signal transduction; Connexin; Osteoblast; Chemistry; In vivo; Biology; In vitro; Intracellular; Gap junction; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000350198,0.0003092371,0.000246677,0.0004035473,0.0005726077,0.0003803968,0.0001289215,0.0002434992,0.002368209],"category_scores_gemma":[0.0002496213,0.0003231979,0.0004164284,0.0002067792,0.0003857794,0.0005446312,0.0006076466,0.0006073331,0.0002616898],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003838548,"about_ca_system_score_gemma":0.0004981055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001329772,"about_ca_topic_score_gemma":0.002999658,"domain_scores_codex":[0.9997039,0.00006356637,0.00002406227,0.00004327952,0.00007170444,0.00009340684],"domain_scores_gemma":[0.9998457,0.00002458367,0.00004290213,0.00001830276,0.00001674467,0.00005169313],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003137068,0.00006374544,0.0004786219,0.00008734467,0.00001576352,0.0002240662,0.00007766914,0.0000801085,0.9957038,0.0007557902,0.0001156641,0.002083714],"study_design_scores_gemma":[0.00005561942,0.0005036803,0.04528754,0.00002895435,0.00004234867,0.0006720084,0.0002984059,0.001202136,0.9449345,0.0005172182,0.006443841,0.0000137085],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915317,0.002745303,0.002061802,0.0002561957,0.00007551062,0.0000188213,0.0001034779,0.00004230925,0.003164853],"genre_scores_gemma":[0.9944192,0.001160836,0.0006676516,0.00003697399,0.00001934925,0.00002742971,0.00009382665,0.000009544751,0.003565173],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002368209,"threshold_uncertainty_score":0.007922471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1097916579957987,"score_gpt":0.3406588838995662,"score_spread":0.2308672259037675,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}