{"id":"W2263317399","doi":"10.1016/j.ccell.2016.01.003","title":"A Word of Caution on New and Revolutionary Diagnostic Tests","year":2016,"lang":"en","type":"letter","venue":"Cancer Cell","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Canada Research Chairs; University Health Network; Mount Sinai Hospital","funders":"","keywords":"Scopus; Cancer; Editorial board; Medicine; Test (biology); MEDLINE; Computer science; Internal medicine; Library science; Political science; Biology; Law","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01384676,0.001406596,0.00297455,0.001187883,0.006348693,0.008753722,0.003729376,0.1111369,0.006917963],"category_scores_gemma":[0.07482696,0.001437238,0.002124665,0.0007112077,0.01676656,0.01283038,0.004793565,0.1327256,0.007514164],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005831836,"about_ca_system_score_gemma":0.006306946,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003694222,"about_ca_topic_score_gemma":0.007860584,"domain_scores_codex":[0.9836923,0.00530267,0.00178986,0.002166076,0.005736603,0.001312574],"domain_scores_gemma":[0.9540505,0.03087655,0.001994022,0.001866478,0.005996034,0.005216355],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007085897,0.00003322297,0.0002825997,0.00008437959,0.00003460831,0.00141002,0.0002841469,0.00007185702,0.0002756821,0.01041741,0.9788271,0.008208153],"study_design_scores_gemma":[0.0001790165,0.00008214417,0.000414059,0.0007707597,0.00003938739,0.001882714,0.0007745814,0.0003601571,0.0002463946,0.05312003,0.9419755,0.0001552936],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00009588488,0.001595488,0.0001783692,0.9776804,0.01921767,0.00000468277,0.00001137461,0.00001442406,0.001201705],"genre_scores_gemma":[0.000962875,0.0005040665,0.0002532308,0.9649895,0.03156849,0.00001100724,0.000005470285,0.00001429243,0.001691136],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.1111369,"threshold_uncertainty_score":0.07322949,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009333269072345678,"score_gpt":0.2329232554608049,"score_spread":0.2235899863884592,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}