{"id":"W2263441127","doi":"10.1128/iai.00912-15","title":"Surface Polysaccharide Mutants Reveal that Absence of O Antigen Reduces Biofilm Formation of Actinobacillus pleuropneumoniae","year":2015,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Actinobacillus pleuropneumoniae; Biofilm; Microbiology; Mutant; Biology; Pasteurellaceae; Virulence; Antigen; Bacterial capsule; Polysaccharide; Bacteria; Lipopolysaccharide; Serotype; Gene; Biochemistry; Immunology; Antibiotics; Haemophilus influenzae; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001144972,0.0004824616,0.0002801591,0.0001726871,0.0000839416,0.0002559906,0.0002074671,0.0003253729,0.0006376946],"category_scores_gemma":[0.000209532,0.0001998348,0.0002999387,0.0001299154,0.0001412754,0.0001385704,0.0002442605,0.0004463173,0.0001777543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001742837,"about_ca_system_score_gemma":0.0001888581,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001323529,"about_ca_topic_score_gemma":0.00102129,"domain_scores_codex":[0.9997566,0.00003940815,0.00002756642,0.00003974011,0.00008798276,0.00004869],"domain_scores_gemma":[0.9998471,0.00002709986,0.00004972528,0.00001665534,0.00002224703,0.00003723293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002933316,0.0000250215,0.0001009744,0.000007947172,0.000002591015,0.00001661852,0.00000766244,0.00001528011,0.9995601,0.00000844861,0.000008881282,0.0002172303],"study_design_scores_gemma":[0.00002047789,0.0007953069,0.02106556,0.00001138253,0.00003057867,0.0002562456,0.0001035575,0.001680011,0.9750729,0.0000451423,0.0009090398,0.000009800151],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986048,0.0002534587,0.0006230961,0.00004187926,0.00001129159,0.00001043083,0.0001437195,0.00002189572,0.0002893816],"genre_scores_gemma":[0.9969139,0.0002119013,0.001185322,0.00004137027,0.000003975568,0.00002059621,0.0004074,0.00001988897,0.001195655],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001323529,"threshold_uncertainty_score":0.002631664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06555858659375073,"score_gpt":0.3058073059708938,"score_spread":0.240248719377143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}