{"id":"W2263441127","doi":"10.1128/iai.00912-15","title":"Surface Polysaccharide Mutants Reveal that Absence of O Antigen Reduces Biofilm Formation of Actinobacillus pleuropneumoniae","year":2015,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Microbial infections and disease research","field":"Immunology and Microbiology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal","funders":"Biotechnology and Biological Sciences Research Council; Natural Sciences and Engineering Research Council of Canada","keywords":"Actinobacillus pleuropneumoniae; Biofilm; Microbiology; Mutant; Biology; Pasteurellaceae; Virulence; Antigen; Bacterial capsule; Polysaccharide; Bacteria; Lipopolysaccharide; Serotype; Gene; Biochemistry; Immunology; Antibiotics; Haemophilus influenzae; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004643345,0.0001088119,0.0002124649,0.0001386841,0.000163324,0.0000143345,0.00007956756,0.0001279118,0.0001077299],"category_scores_gemma":[0.0001547737,0.00009815345,0.00006111353,0.0002421014,0.0002463002,0.000293461,0.00009448308,0.0002112479,0.00003975939],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003232298,"about_ca_system_score_gemma":0.00009154933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004152892,"about_ca_topic_score_gemma":0.00005388663,"domain_scores_codex":[0.9990714,0.0003072567,0.0002710703,0.0001215423,0.00004987706,0.0001788588],"domain_scores_gemma":[0.9992502,0.00006713882,0.0002030977,0.0002010595,0.000235242,0.00004330508],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001154969,0.0001439158,0.02562501,0.00003890345,0.00003922622,4.512685e-7,0.0004355987,0.00001292072,0.9707449,0.00004096704,0.0003141157,0.002488484],"study_design_scores_gemma":[0.0006070102,0.0002118752,0.05822567,0.0000434122,0.00001400078,0.00008510442,0.0004236592,0.00001557421,0.9392004,0.00005276273,0.001021183,0.00009936644],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976335,0.000763619,0.0001122294,0.00003526931,0.0003158815,0.0001594288,0.00006042067,0.00003527181,0.0008844442],"genre_scores_gemma":[0.9989384,0.0007717061,0.00001711218,0.00001031649,0.000007465123,0.000002109496,0.00002896094,0.000006484511,0.0002174775],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03260066,"threshold_uncertainty_score":0.6277958,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06555858659375073,"score_gpt":0.3058073059708938,"score_spread":0.240248719377143,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}