{"id":"W2264170040","doi":"10.1038/ng.3500","title":"MYB-QKI rearrangements in angiocentric glioma drive tumorigenicity through a tripartite mechanism","year":2016,"lang":"en","type":"review","venue":"Nature Genetics","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":281,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre; Montreal Children's Hospital; Hospital for Sick Children","funders":"National Institute of General Medical Sciences; National Institute of Neurological Disorders and Stroke; National Human Genome Research Institute; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Biology; MYB; Carcinogenesis; Enhancer; Cancer research; Chromosomal translocation; Epigenetics; Glioma; Genetics; Transcription factor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001766713,0.0003614608,0.0004869203,0.0004543411,0.00006760598,0.0003301445,0.0002836929,0.0003947651,0.001353019],"category_scores_gemma":[0.0001867176,0.0001179877,0.0001472338,0.0003529759,0.0002189476,0.0004155982,0.0003397862,0.0007698412,0.0007053132],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000315522,"about_ca_system_score_gemma":0.0004357803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002702381,"about_ca_topic_score_gemma":0.0007268864,"domain_scores_codex":[0.999951,0.000006054036,0.000006790216,0.00001155475,0.00001759459,0.000006998536],"domain_scores_gemma":[0.9999452,0.00001920061,0.00001637946,0.000001824006,0.00001109544,0.000006443185],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000134152,0.00002472359,0.0006228171,0.006103291,0.00009561954,0.0004837968,0.00004155986,0.0003463882,0.02046649,0.00433856,0.01821,0.9491327],"study_design_scores_gemma":[0.00005942422,0.0001275173,0.002684648,0.001370664,0.0002245778,0.004174647,0.00005738124,0.0002816001,0.006285736,0.003396183,0.981311,0.00002666176],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001485319,0.9943162,0.0009655553,0.0008198782,0.0002588198,0.000007806362,0.0000476575,0.0000267936,0.00207195],"genre_scores_gemma":[0.01233308,0.9834802,0.0009903162,0.0005283192,0.0002652341,0.00001532206,0.000114916,0.000004134729,0.002268373],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.001353019,"threshold_uncertainty_score":0.004526317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02997616947552383,"score_gpt":0.3440623624264995,"score_spread":0.3140861929509756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}