{"id":"W2264871965","doi":"10.1038/ncomms10368","title":"A Drosophila RNAi library modulates Hippo pathway-dependent tissue growth","year":2016,"lang":"en","type":"article","venue":"Nature Communications","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Cancer Council Victoria; Institute of Genetics; National Health and Medical Research Council; Medical Research Council","keywords":"RNA interference; Drosophila melanogaster; Ectopic expression; Biology; Hippo signaling pathway; Genetic screen; Phenotype; Transgene; Transcription factor; Genetics; Computational biology; Cell biology; Gene; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002233684,0.0007689272,0.0004240385,0.0009705737,0.0004005068,0.0003809001,0.0004540306,0.0004282915,0.00254159],"category_scores_gemma":[0.0001373376,0.0003646146,0.000443119,0.0005040416,0.0003181412,0.0001969881,0.0003747024,0.0007404061,0.001030258],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005427033,"about_ca_system_score_gemma":0.0003586393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001287749,"about_ca_topic_score_gemma":0.003687126,"domain_scores_codex":[0.9997054,0.00003221588,0.00005184602,0.00007614428,0.00008641923,0.00004800266],"domain_scores_gemma":[0.9997829,0.00004648291,0.00005726428,0.00003631271,0.00002804311,0.00004919547],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002500774,0.00001922043,0.00007570423,0.00002245333,0.000005558315,0.00003992678,0.000009891265,0.00003125109,0.9987406,0.00006140657,0.00006720245,0.0009018063],"study_design_scores_gemma":[0.00002409231,0.0001294514,0.00310365,0.000009983314,0.00004045796,0.0002267125,0.0000197546,0.0005289361,0.9915337,0.00002235004,0.004352244,0.000008716417],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.949157,0.001482723,0.02652091,0.0003109498,0.00008984071,0.0006272727,0.00831335,0.001577479,0.01192038],"genre_scores_gemma":[0.922893,0.002500725,0.03250355,0.0003448068,0.00003085778,0.0006442551,0.01731469,0.0007081087,0.02305994],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00254159,"threshold_uncertainty_score":0.008502483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01134992809974325,"score_gpt":0.2538348579446479,"score_spread":0.2424849298449046,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}