{"id":"W2265087310","doi":"10.1200/jco.2007.25.18_suppl.14535","title":"Effect of hyperthermia on the pharmacokinetic profile of oxaliplatin administered by intraperitoneal route in rats","year":2007,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Treatment and Pharmacology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Oxaliplatin; Medicine; Peritoneum; Pharmacokinetics; Hyperthermia; Perfusion; Intraperitoneal injection; Mesentery; In vivo; Chemotherapy; Pharmacology; Surgery; Internal medicine; Cancer; Colorectal cancer; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002186309,0.0005641785,0.000346068,0.0004018641,0.0001281423,0.0002188637,0.0001675498,0.0002443572,0.001213665],"category_scores_gemma":[0.0002008204,0.0002106505,0.0003733939,0.0001755692,0.0003731643,0.0003262348,0.0001569385,0.0007370808,0.0002425391],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003549354,"about_ca_system_score_gemma":0.0003280162,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008254597,"about_ca_topic_score_gemma":0.00121304,"domain_scores_codex":[0.9998362,0.00002657292,0.00000922719,0.0000355427,0.00003908482,0.00005339715],"domain_scores_gemma":[0.999774,0.0000337805,0.00009780989,0.00002616342,0.00002174738,0.00004649145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002820724,0.0003205564,0.001191901,0.0000492984,0.00002270315,0.00006052887,0.00005981154,0.0002161368,0.9912295,0.00006741738,0.00009058823,0.003870853],"study_design_scores_gemma":[0.00008853515,0.01311968,0.01302638,0.00000877572,0.00007241772,0.000152694,0.00005860349,0.001158756,0.970899,0.00005662149,0.001339796,0.00001872044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969378,0.0008811894,0.001379598,0.0000537158,0.00002666584,0.00003376553,0.0002182739,0.00007805019,0.0003910185],"genre_scores_gemma":[0.9949234,0.001035216,0.001950768,0.00005189703,0.0000227421,0.00009303149,0.0003680063,0.00002137984,0.00153346],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001213665,"threshold_uncertainty_score":0.004060149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08793512567251474,"score_gpt":0.5115380316999573,"score_spread":0.4236029060274425,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}