{"id":"W2265325729","doi":"10.1182/blood.v124.21.3764.3764","title":"A Phase 1 Study of Azacitidine (AZA) in Combination with Fludarabine and Cytarabine in Relapse/Refractory Childhood Leukemia: A Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) Study","year":2014,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Medicine; Cytarabine; Fludarabine; Acute myeloblastic leukemia; Leukemia; Decitabine; Internal medicine; Oncology; Childhood leukemia; Refractory (planetary science); Chemotherapy; Azacitidine; Gastroenterology; DNA methylation; Cyclophosphamide; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002370898,0.001668096,0.002415241,0.0006789494,0.0005596373,0.0009925403,0.001323793,0.001248939,0.002834049],"category_scores_gemma":[0.000806304,0.0006621422,0.00129808,0.000537728,0.0009879769,0.0006019587,0.0003832713,0.003233771,0.0007529451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001103745,"about_ca_system_score_gemma":0.002497056,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002024167,"about_ca_topic_score_gemma":0.00398744,"domain_scores_codex":[0.999325,0.0003593011,0.00002695516,0.0001071136,0.00007287298,0.0001087933],"domain_scores_gemma":[0.9991943,0.000109374,0.0001320593,0.00007001492,0.00005931241,0.0004348345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5432088,0.2333639,0.01511204,0.001136984,0.001874273,0.0009880153,0.0005820983,0.003294201,0.1045354,0.0003830177,0.004245675,0.09127558],"study_design_scores_gemma":[0.4401714,0.5386935,0.01212428,0.00002982452,0.0005121681,0.0004084213,0.00006895568,0.0008708651,0.005112899,0.00008443334,0.001899177,0.00002397867],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926778,0.001354364,0.0003755093,0.0003455163,0.00006063963,0.003422123,0.0007299623,0.00006886498,0.0009652853],"genre_scores_gemma":[0.9835333,0.002664499,0.002729571,0.0008790261,0.0002105076,0.004692243,0.002419586,0.00004169549,0.002829569],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002834049,"threshold_uncertainty_score":0.01253861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01128326579143368,"score_gpt":0.2820521748959951,"score_spread":0.2707689091045614,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}