{"id":"W2265477132","doi":"10.1002/1873-3468.12037","title":"Proteomic peptide phage display uncovers novel interactions of the PDZ1‐2 supramodule of syntenin","year":2015,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Vlaamse regering; Vetenskapsrådet; Canadian Institutes of Health Research; KU Leuven; Fonds Wetenschappelijk Onderzoek; Institut National de la Santé et de la Recherche Médicale; Åke Wiberg Stiftelse","keywords":"Phage display; Peptide library; PDZ domain; Postsynaptic density; Proteome; Peptide; Cleave; Human proteome project; Chemistry; Computational biology; Cell biology; Proteomics; Biology; Peptide sequence; Biochemistry; Postsynaptic potential; Enzyme; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006421915,0.0002075955,0.0001295803,0.0001710793,0.0001262873,0.0002667183,0.0001135097,0.0001829527,0.0007668874],"category_scores_gemma":[0.00007432495,0.00008809274,0.0001131754,0.0001259789,0.0001322267,0.0001066264,0.0001993013,0.0002791263,0.0002915696],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001714471,"about_ca_system_score_gemma":0.00007137081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002081155,"about_ca_topic_score_gemma":0.0003801946,"domain_scores_codex":[0.999952,0.000004586772,0.000001753466,0.00001227063,0.00001613723,0.00001332355],"domain_scores_gemma":[0.9999673,0.000007870714,0.000006528575,0.00000243689,0.000003994177,0.0000117015],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003784316,0.000007608137,0.0002375118,0.000005664628,0.000001987455,0.00003399944,0.000006590476,0.00003318854,0.9991964,0.00003094704,0.00001991972,0.0003882991],"study_design_scores_gemma":[0.000006434548,0.00009853462,0.01174468,0.000001796712,0.000009845801,0.0003902271,0.00003566302,0.00236397,0.9844081,0.00007153652,0.0008642597,0.000004852181],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973647,0.0001292452,0.00169456,0.00003217201,0.000003117821,0.00000525104,0.0001288055,0.00002088704,0.0006213254],"genre_scores_gemma":[0.9958675,0.0001490508,0.001810404,0.00005616314,0.000003488065,0.000008743751,0.0004071915,0.00001476646,0.001682714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007668874,"threshold_uncertainty_score":0.002565444,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01734385712945113,"score_gpt":0.2401918126873399,"score_spread":0.2228479555578888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}