{"id":"W2265477132","doi":"10.1002/1873-3468.12037","title":"Proteomic peptide phage display uncovers novel interactions of the PDZ1‐2 supramodule of syntenin","year":2015,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Hippo pathway signaling and YAP/TAZ","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Vlaamse regering; Vetenskapsrådet; Canadian Institutes of Health Research; KU Leuven; Fonds Wetenschappelijk Onderzoek; Institut National de la Santé et de la Recherche Médicale; Åke Wiberg Stiftelse","keywords":"Phage display; Peptide library; PDZ domain; Postsynaptic density; Proteome; Peptide; Cleave; Human proteome project; Chemistry; Computational biology; Cell biology; Proteomics; Biology; Peptide sequence; Biochemistry; Postsynaptic potential; Enzyme; Receptor; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001597341,0.0001098907,0.0001294545,0.0000299203,0.00003476702,0.000007399511,0.0002278183,0.00005397746,0.000008030648],"category_scores_gemma":[0.0001340267,0.00008262724,0.0001312491,0.00008165433,0.0001209098,0.000005273735,0.00008061444,0.0001033075,0.000006703941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001935312,"about_ca_system_score_gemma":0.00006442484,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000144206,"about_ca_topic_score_gemma":0.00002732346,"domain_scores_codex":[0.9992759,0.00004887237,0.0001990828,0.0001833745,0.0001432797,0.0001494957],"domain_scores_gemma":[0.999374,0.00001256523,0.0001449864,0.0003487805,0.00006630777,0.00005330324],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005765626,0.00005534665,0.003760377,0.00001568191,0.00004634716,7.589829e-7,0.0001671767,0.0008805607,0.9928883,0.0000158337,0.002061562,0.00005043761],"study_design_scores_gemma":[0.0004909493,0.000090006,0.001459221,0.00004428309,0.00002353857,0.0000117775,0.0000949369,0.00007548056,0.9897906,0.000006380903,0.007811036,0.0001018272],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954388,0.00002460692,0.002831599,0.0007706963,0.0002958952,0.0001692541,0.0000774007,0.000006260956,0.0003854765],"genre_scores_gemma":[0.9981561,0.000001682379,0.000687704,0.0005120015,0.0001074622,0.00001480958,0.00003182499,0.00001577807,0.0004726438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005749474,"threshold_uncertainty_score":0.3369441,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01734385712945113,"score_gpt":0.2401918126873399,"score_spread":0.2228479555578888,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}