{"id":"W2266505172","doi":"10.1007/978-1-62703-128-8_8","title":"In Vitro Generation of Human T Regulatory Cells: Generation, Culture, and Analysis of FOXP3-Transduced T Cells","year":2012,"lang":"en","type":"article","venue":"Methods in molecular biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"FOXP3; Ex vivo; Immune system; Immunology; In vitro; Biology; Cell biology; Phenotype; Regulatory T cell; Transcription factor; IL-2 receptor; Cancer research; T cell; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005273698,0.0004241592,0.0003615701,0.0002703289,0.0002301549,0.0004216993,0.0003086048,0.0003048757,0.002212756],"category_scores_gemma":[0.0002169501,0.0001885149,0.0002918741,0.0002930248,0.0002307209,0.000158023,0.0002571859,0.000879416,0.001543222],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001599325,"about_ca_system_score_gemma":0.0002360435,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003156556,"about_ca_topic_score_gemma":0.0004776138,"domain_scores_codex":[0.999668,0.00007737353,0.00004345887,0.00006571875,0.0001007647,0.00004463582],"domain_scores_gemma":[0.9998847,0.00003451774,0.00001847933,0.00002850366,0.00001851168,0.00001527424],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006867429,0.00004865344,0.0001309171,0.00008548699,0.000003515682,0.00006206282,0.00002897936,0.000167013,0.9961377,0.000170968,0.0001362309,0.002959789],"study_design_scores_gemma":[0.00002231762,0.0002138296,0.0006011742,0.00001099981,0.00001779948,0.0002513334,0.00001037848,0.0005143486,0.9887444,0.00006550831,0.009542549,0.000005479683],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"methods","genre_scores_codex":[0.5915937,0.01248805,0.3636365,0.0004424217,0.0007194745,0.00229852,0.009957229,0.001639721,0.01722433],"genre_scores_gemma":[0.7962272,0.01221348,0.16083,0.0005003513,0.0002395643,0.002436602,0.01219369,0.0004888271,0.01487032],"genre_candidate":"methods","genre_consensus":null,"teacher_disagreement_score":0.002212756,"threshold_uncertainty_score":0.00740242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03029027202667068,"score_gpt":0.3490666920658019,"score_spread":0.3187764200391312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}