{"id":"W2266524926","doi":"10.1016/j.ebiom.2016.02.015","title":"The BuMPy Road to COPD Gene Discovery","year":2016,"lang":"en","type":"letter","venue":"EBioMedicine","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital","funders":"","keywords":"COPD; Medicine; Genome-wide association study; Genetics; Population; Imputation (statistics); Pulmonary disease; Bioinformatics; Gene; Biology; Internal medicine; Single-nucleotide polymorphism; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03649277,0.00149607,0.004227842,0.00572787,0.00214604,0.008786278,0.003898972,0.01006489,0.03036307],"category_scores_gemma":[0.09198997,0.001018828,0.002729196,0.003894055,0.006415865,0.01423321,0.00704862,0.02618372,0.01598877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004027559,"about_ca_system_score_gemma":0.01227958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005260992,"about_ca_topic_score_gemma":0.005905126,"domain_scores_codex":[0.9853395,0.006403727,0.001113147,0.002038773,0.003664674,0.001440076],"domain_scores_gemma":[0.8837306,0.06393421,0.00243907,0.00908112,0.02743699,0.01337807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003562774,0.0001135197,0.001435191,0.002051363,0.0002385393,0.0004792849,0.0004946342,0.0002653364,0.0009748907,0.041593,0.6650255,0.2869726],"study_design_scores_gemma":[0.0001259508,0.000182578,0.001717091,0.00437916,0.0001207474,0.0006233961,0.0004872329,0.0005896625,0.000293017,0.1156601,0.8757185,0.0001026212],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.00184961,0.2205984,0.01459986,0.7050721,0.04429214,0.000120392,0.002045571,0.0009917925,0.01043011],"genre_scores_gemma":[0.02803745,0.394771,0.04944894,0.3920969,0.1052411,0.0006516777,0.006244366,0.001324975,0.02218362],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.03649277,"threshold_uncertainty_score":0.1929945,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01705063741196717,"score_gpt":0.3008322981830278,"score_spread":0.2837816607710607,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}