{"id":"W2266877858","doi":"","title":"Increase of therapeutic effects by treating melanoma with targeted combinations of c-myc antisense and doxorubicin.","year":2007,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Propidium iodide; Melanoma; In vivo; Doxorubicin; In vitro; Apoptosis; Cancer research; Annexin; Pharmacology; MTT assay; Medicine; Chemistry; Chemotherapy; Molecular biology; Biology; Programmed cell death; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008194026,0.0002949498,0.0001991704,0.0002226638,0.00006980311,0.0001601648,0.0001014883,0.0001682953,0.001357509],"category_scores_gemma":[0.0000756064,0.00006747658,0.0001060802,0.00009484008,0.00008695351,0.0001087898,0.0001139548,0.0002444518,0.00021247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001262725,"about_ca_system_score_gemma":0.00008784678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002907817,"about_ca_topic_score_gemma":0.0005736109,"domain_scores_codex":[0.9999404,0.0000134628,0.000004324071,0.00001556258,0.00001180132,0.00001450883],"domain_scores_gemma":[0.9999654,0.000008492266,0.000006529758,0.000003789318,0.000004481246,0.00001122003],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002003339,0.00008725865,0.0002298828,0.00005369649,0.000008706003,0.000032268,0.00001203929,0.0001140227,0.9920799,0.00008987592,0.0001279052,0.006964066],"study_design_scores_gemma":[0.00009038559,0.004115718,0.005420251,0.00001229399,0.00005159967,0.0004642757,0.00002351747,0.001424505,0.9807019,0.00004840651,0.00764169,0.000005493208],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896248,0.003572675,0.001780188,0.00009763551,0.00007056534,0.00008583932,0.0002198243,0.0001110182,0.004437515],"genre_scores_gemma":[0.995112,0.000930154,0.001874271,0.00003864096,0.00001480417,0.00003705929,0.0001713323,0.00001268583,0.001809065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001357509,"threshold_uncertainty_score":0.004541278,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006366709458148614,"score_gpt":0.2506000983877784,"score_spread":0.2442333889296298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}