{"id":"W2266877858","doi":"","title":"Increase of therapeutic effects by treating melanoma with targeted combinations of c-myc antisense and doxorubicin.","year":2007,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Propidium iodide; Melanoma; In vivo; Doxorubicin; In vitro; Apoptosis; Cancer research; Annexin; Pharmacology; MTT assay; Medicine; Chemistry; Chemotherapy; Molecular biology; Biology; Programmed cell death; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001329461,0.0001713144,0.0002168426,0.00005976774,0.00004115671,0.000008065445,0.0001118098,0.0001096821,0.000004423751],"category_scores_gemma":[0.000007429662,0.0001460321,0.00005821987,0.0001351726,0.0001559917,0.000004342021,0.00003358771,0.00006823066,2.792133e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001145273,"about_ca_system_score_gemma":0.0000559081,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001809701,"about_ca_topic_score_gemma":0.00005724702,"domain_scores_codex":[0.9991313,0.00006194557,0.0002273582,0.0002280258,0.0001485494,0.0002028599],"domain_scores_gemma":[0.9993421,0.00003235221,0.0001594675,0.000252396,0.0001583232,0.00005531905],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002589105,0.0001505328,0.01077472,0.00005074689,0.0003535479,0.000008214332,0.0001274304,0.00001590247,0.9757503,0.00009764514,0.00002080885,0.01239126],"study_design_scores_gemma":[0.001389311,0.0009942497,0.005885795,0.00005667653,0.0001548498,0.00001023033,0.00009633676,0.00007042917,0.9904986,0.00005691085,0.0006173369,0.0001692588],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9763886,0.01381065,0.009219651,0.0000488007,0.0000365571,0.0002027246,0.00003398363,0.00000676357,0.0002522751],"genre_scores_gemma":[0.9981946,0.000826576,0.0003776444,0.00042778,0.00001514368,0.00001061085,0.00004768547,0.00002766636,0.00007230151],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.021806,"threshold_uncertainty_score":0.5955015,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006366709458148614,"score_gpt":0.2506000983877784,"score_spread":0.2442333889296298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}