{"id":"W2267101752","doi":"10.2147/copd.s95055","title":"The lung function profile of once-daily tiotropium and olodaterol via Respimat® is superior to that of twice-daily salmeterol and luticasone propionate via Accuhaler® (ENERGITO® study)","year":2016,"lang":"en","type":"article","venue":"International Journal of COPD","topic":"Chronic Obstructive Pulmonary Disease (COPD) Research","field":"Medicine","cited_by":106,"is_retracted":false,"has_abstract":true,"ca_institutions":"Boehringer Ingelheim (Canada)","funders":"Apellis Pharmaceuticals; Ablynx; CSL Behring; Teva Pharmaceutical Industries; AstraZeneca; Pfizer","keywords":"Fluticasone propionate; Salmeterol; Medicine; COPD; Tiotropium bromide; Exacerbation; Fluticasone; Anesthesia; Internal medicine; Corticosteroid; Lung; Lung function","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001002615,0.0004429146,0.0008204262,0.0006828643,0.0001789373,0.0001240978,0.0006732222,0.0001729074,0.0007264827],"category_scores_gemma":[0.000613267,0.0002838071,0.0002751699,0.000314352,0.0005390036,0.0006244296,0.0004481079,0.0004912301,0.00006159051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005734428,"about_ca_system_score_gemma":0.0004260538,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001699388,"about_ca_topic_score_gemma":0.0001589096,"domain_scores_codex":[0.9947847,0.0003785954,0.001312944,0.0005908022,0.002375956,0.000556996],"domain_scores_gemma":[0.9950947,0.0005980945,0.0008792988,0.0006566331,0.002257641,0.0005136732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.03209119,0.00229142,0.353445,0.0007759521,0.00417882,0.0001957562,0.00293938,0.00002987785,0.4691463,0.0002498668,0.01966607,0.1149903],"study_design_scores_gemma":[0.01769544,0.002973916,0.853867,0.00230826,0.0009416276,0.001855144,0.0008289609,0.000373419,0.01440136,0.0008544995,0.1031192,0.0007811793],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9828213,0.002036778,0.004829817,0.007722499,0.0009248146,0.001242785,0.0002016177,0.00002684772,0.0001934772],"genre_scores_gemma":[0.992672,0.0005672306,0.001767207,0.0003206976,0.0006632318,0.00007045622,0.00002647594,0.00007580696,0.003836909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5004219,"threshold_uncertainty_score":0.9999614,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03004997221063099,"score_gpt":0.3275731076911075,"score_spread":0.2975231354804765,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}