{"id":"W2267593360","doi":"10.1182/blood.v96.13.4160","title":"During ontogeny primitive (CD34+CD38−) hematopoietic cells show altered expression of a subset of genes associated with early cytokine and differentiation responses of their adult counterparts","year":2000,"lang":"en","type":"article","venue":"Blood","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":63,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Biology; CD38; Haematopoiesis; CD34; Stem cell factor; Bone marrow; Hematopoietic growth factor; Cord blood; Stem cell; Cytokine; Growth factor; Cell biology; Immunology; Molecular biology; Receptor; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001316225,0.0001853942,0.0005355318,0.0001154858,0.00003192762,0.000006163696,0.00006144564,0.0001086584,0.00008012696],"category_scores_gemma":[0.00003647717,0.0001414656,0.00006819142,0.0001389802,0.0001075522,0.0000742823,0.00001121581,0.00007500443,7.878622e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001582568,"about_ca_system_score_gemma":0.00005098496,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004294426,"about_ca_topic_score_gemma":0.00003031777,"domain_scores_codex":[0.9985865,0.0001270153,0.0005067072,0.0002368285,0.0003668862,0.0001761087],"domain_scores_gemma":[0.9988643,0.0002469809,0.0003303954,0.0002406993,0.0002464629,0.00007116219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0016497,0.0006568027,0.1449845,0.0007870988,0.000167174,0.00001116692,0.004766336,0.000002524101,0.8469134,0.000004933127,0.000001630058,0.00005473931],"study_design_scores_gemma":[0.003853812,0.0003799219,0.375531,0.001859694,0.0002836327,0.00003287433,0.0001841312,0.00001569961,0.6177785,0.000005473093,3.519725e-7,0.00007488758],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988438,0.0001824639,0.00004265611,0.0000152714,0.00001665471,0.0005135147,0.0002412702,0.00002405146,0.0001203348],"genre_scores_gemma":[0.9993288,0.0002214441,0.0002288627,0.000007230148,0.00001586871,0.00001848392,0.00006314136,0.00002712673,0.00008904708],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2305465,"threshold_uncertainty_score":0.57688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01092414660345851,"score_gpt":0.2186596180100374,"score_spread":0.2077354714065789,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}