{"id":"W2267972339","doi":"10.1371/journal.pone.0147978","title":"Conditioned Medium from Early-Outgrowth Bone Marrow Cells Is Retinal Protective in Experimental Model of Diabetes","year":2016,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"Fakultet Medicinskih Nauka, Univerziteta U Kragujevcu; Conselho Nacional de Desenvolvimento Científico e Tecnológico; Fundação de Amparo à Pesquisa do Estado de São Paulo","keywords":"Diabetic retinopathy; Bone marrow; NADPH oxidase; Retinal; Medicine; Retina; Diabetes mellitus; Reactive oxygen species; Internal medicine; Endocrinology; Oxidative stress; Chemistry; Biology; Ophthalmology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006889779,0.0001213477,0.0001779355,0.00004337524,0.00002221537,0.00000585422,0.0001026461,0.0001032789,0.000109676],"category_scores_gemma":[0.00003171902,0.0000995001,0.00004329863,0.00004183115,0.00009664769,0.000007211693,0.0000679652,0.00004460458,0.00001606056],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001692729,"about_ca_system_score_gemma":0.00004574272,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002284606,"about_ca_topic_score_gemma":0.000006613457,"domain_scores_codex":[0.9991258,0.00003339615,0.0001984584,0.00026786,0.0001932111,0.000181244],"domain_scores_gemma":[0.9996475,0.00001280095,0.00008445004,0.0001527198,0.00005326384,0.00004925381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001475259,0.0004249543,0.02097472,0.00001512607,0.00006890744,5.699841e-7,0.0002008942,5.882911e-7,0.9779608,0.000008350853,0.0001719042,0.00002564815],"study_design_scores_gemma":[0.001004796,0.000226155,0.007111722,0.0001044538,0.00001435752,3.853599e-8,0.00006199671,0.00006440668,0.9905809,0.0006717109,0.000005069366,0.0001543508],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9984885,0.0002047838,0.0001457016,0.0002415818,0.00001448101,0.0002736108,0.00008074148,0.000007084334,0.0005435119],"genre_scores_gemma":[0.9978384,0.00003632339,0.001469874,0.00008661163,0.00003465494,0.00009260408,0.00005016932,0.00001580579,0.0003755224],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.013863,"threshold_uncertainty_score":0.4057496,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01542672414612818,"score_gpt":0.2046124747157801,"score_spread":0.1891857505696519,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}