{"id":"W2268398524","doi":"10.1038/ncomms9388","title":"PTEN regulates cilia through Dishevelled","year":2015,"lang":"en","type":"article","venue":"Nature Communications","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Ontario Ministry of Research and Innovation; Canadian Institutes of Health Research","keywords":"PTEN; Cilium; Dishevelled; Ciliogenesis; Tensin; Cell biology; Biology; Motile cilium; Wnt signaling pathway; Centrosome; PI3K/AKT/mTOR pathway; Signal transduction; Frizzled; Genetics; Cell cycle; Cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001603804,0.0003427362,0.0001484716,0.000418566,0.0003059285,0.0006414054,0.0002875995,0.000231593,0.001332446],"category_scores_gemma":[0.0002077303,0.000169748,0.0002626454,0.0002115724,0.0004444994,0.0002424165,0.0005491527,0.0003511453,0.0006264971],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005840294,"about_ca_system_score_gemma":0.000416558,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001601415,"about_ca_topic_score_gemma":0.001759562,"domain_scores_codex":[0.9997326,0.00002773,0.00001632678,0.00004118904,0.0001083227,0.00007390267],"domain_scores_gemma":[0.9998825,0.00001252586,0.00003401902,0.000007928278,0.00001573608,0.00004738137],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001285365,0.00001267337,0.0007696461,0.00006406803,0.000009270366,0.0004209198,0.00003578504,0.0001961116,0.9944662,0.001176635,0.0002600666,0.002460113],"study_design_scores_gemma":[0.0000492757,0.0001324442,0.02280283,0.00001056041,0.00004228495,0.0009420097,0.0001346394,0.00343908,0.9529335,0.0006530451,0.01884279,0.00001748618],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9703802,0.006196987,0.00831235,0.0008406645,0.0001927045,0.00004671737,0.0008803311,0.0005987819,0.01255119],"genre_scores_gemma":[0.9935994,0.001172424,0.0007581769,0.00007707468,0.00001364625,0.000009906684,0.0002121577,0.00001970005,0.004137591],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001601415,"threshold_uncertainty_score":0.004457414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02627216151624005,"score_gpt":0.3064441661890397,"score_spread":0.2801720046727996,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}