{"id":"W2268718167","doi":"10.1021/acs.chemrestox.5b00323","title":"Similarities between <i>N</i>-Acetylcysteine and Glutathione in Binding to Lead(II) Ions","year":2015,"lang":"en","type":"article","venue":"Chemical Research in Toxicology","topic":"Heavy Metal Exposure and Toxicity","field":"Environmental Science","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Basic Energy Sciences; National Institute of General Medical Sciences; Biological and Environmental Research; Government of Alberta; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; University of Calgary","keywords":"Acetylcysteine; Glutathione; Chemistry; Lead (geology); Ion; Combinatorial chemistry; Biochemistry; Antioxidant; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002769785,0.0001163528,0.0002901011,0.0001998352,0.00007709702,0.00002037382,0.0002850218,0.0002243875,0.0001088822],"category_scores_gemma":[0.001790389,0.0001111742,0.00002070732,0.0008912438,0.0005487608,0.0001336912,0.001093445,0.0006806089,0.0002278548],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004845813,"about_ca_system_score_gemma":0.00005738183,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003625879,"about_ca_topic_score_gemma":0.0003954697,"domain_scores_codex":[0.9977208,0.0003119672,0.0003044848,0.0004259434,0.0004658707,0.000770886],"domain_scores_gemma":[0.9987247,0.0005565257,0.00001827605,0.0001948748,0.00001579952,0.0004898527],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001053127,0.0002665983,0.07998709,0.0000222371,0.000005548113,0.0001021957,0.001879861,0.00006024476,0.9057373,0.0002463861,0.00394609,0.007641175],"study_design_scores_gemma":[0.004198351,0.002361625,0.05961055,0.0001508428,0.000008869905,0.00004936109,0.002202878,0.0005912208,0.8651496,0.01457503,0.05025056,0.0008511096],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850459,0.00005646082,0.00001704896,0.005975535,0.00003673624,0.0003001808,0.000008384096,0.00001646295,0.008543336],"genre_scores_gemma":[0.998318,0.00001498618,0.0008603056,0.0002528249,0.00006429115,0.00006636321,0.00000519744,0.00001085729,0.000407227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04630447,"threshold_uncertainty_score":0.4533552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1965679194382307,"score_gpt":0.4052005710957205,"score_spread":0.2086326516574898,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}