{"id":"W2269076962","doi":"10.2337/dbi15-0037","title":"Response to Comment on Patel et al. ACE2 Deficiency Worsens Epicardial Adipose Tissue Inflammation and Cardiac Dysfunction in Response to Diet-Induced Obesity. Diabetes 2016;65:85–95","year":2016,"lang":"en","type":"letter","venue":"Diabetes","topic":"Cardiovascular Disease and Adiposity","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Adipose tissue; Epicardial adipose tissue; Inflammation; Internal medicine; Diabetes mellitus; Medicine; Obesity; Endocrinology; Cardiac function curve; Epicardial fat; Heart failure; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001668608,0.001203361,0.001820409,0.0008221337,0.001603784,0.002241627,0.002392961,0.0271962,0.009127742],"category_scores_gemma":[0.01316853,0.0005937008,0.001362577,0.0005817528,0.001836385,0.003089431,0.001117445,0.02671523,0.01151481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003136027,"about_ca_system_score_gemma":0.001282094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002568259,"about_ca_topic_score_gemma":0.002901141,"domain_scores_codex":[0.9987838,0.0003220686,0.0001739258,0.0001836515,0.0003551923,0.0001814209],"domain_scores_gemma":[0.9975949,0.00106638,0.0002372431,0.00009541037,0.0005921473,0.0004139365],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001508556,0.00005078067,0.0005459621,0.00009318837,0.00002106546,0.003437674,0.00007181796,0.0000492728,0.0001738886,0.0006717294,0.9887797,0.00595406],"study_design_scores_gemma":[0.0003482393,0.0002854265,0.00384787,0.0006319103,0.00009154949,0.01340546,0.0004737135,0.0008107646,0.0007247893,0.004658799,0.9745786,0.0001429509],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0007367388,0.002482621,0.0001662931,0.907162,0.08716192,0.00004082602,0.0001795298,0.0001500011,0.001919982],"genre_scores_gemma":[0.005953647,0.00193354,0.0002477545,0.848379,0.1348223,0.00007590936,0.0001024194,0.00005269191,0.008432773],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.0271962,"threshold_uncertainty_score":0.03053534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01106592085767809,"score_gpt":0.2477051801524565,"score_spread":0.2366392592947784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}