{"id":"W2269197281","doi":"10.1093/molehr/gaw008","title":"Whole exome sequencing in recurrent early pregnancy loss","year":2016,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Reproductive System and Pregnancy","field":"Immunology and Microbiology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"Child and Family Research Institute; University of British Columbia","funders":"Canadian Institutes of Health Research; University of California, Santa Cruz","keywords":"Biology; Exome sequencing; Pregnancy; Genetics; Exome; Computational biology; Bioinformatics; Mutation; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006248712,0.0003932231,0.0003699825,0.001173096,0.0002873859,0.0004873572,0.0003120087,0.0006635364,0.001898645],"category_scores_gemma":[0.00144728,0.0001744091,0.0004336313,0.0007141822,0.0001712177,0.0001868456,0.0007005489,0.0002909315,0.0004852944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002586507,"about_ca_system_score_gemma":0.000173434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006162293,"about_ca_topic_score_gemma":0.0008589195,"domain_scores_codex":[0.9996105,0.00007349586,0.00003091154,0.0001364914,0.0001035141,0.00004508287],"domain_scores_gemma":[0.9995847,0.0001787385,0.00008773297,0.00005950287,0.00005096015,0.00003829203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00275631,0.000210238,0.2427365,0.001251984,0.0009315397,0.02868775,0.001142525,0.004540603,0.5367942,0.001526852,0.008449364,0.1709721],"study_design_scores_gemma":[0.0002341877,0.0007192893,0.693515,0.0003430747,0.0009315838,0.08349548,0.0004087664,0.01447379,0.1534792,0.003491726,0.0488163,0.00009160273],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770927,0.003327802,0.01039281,0.0003448825,0.0000440196,0.0000907622,0.006409754,0.000189641,0.002107541],"genre_scores_gemma":[0.9726267,0.001796774,0.01287632,0.0004316243,0.00003752729,0.0001510767,0.009994239,0.0001116118,0.001974],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001898645,"threshold_uncertainty_score":0.00635159,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02121042481909677,"score_gpt":0.2547431093548428,"score_spread":0.233532684535746,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}