{"id":"W2269231033","doi":"","title":"Toxicology and pharmacokinetics of chimeric ARH460-16-2, a therapeutic monoclonal antibody targeting CD44","year":2007,"lang":"en","type":"article","venue":"Molecular Cancer Therapeutics","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Arius3D (Canada)","funders":"","keywords":"Monoclonal antibody; Prostate; Cancer; Biology; Antibody; CD44; Medicine; Colorectal cancer; Pathology; Cancer research; Immunology; Internal medicine; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003594666,0.0004592805,0.0005144711,0.0003217858,0.0001837609,0.0004878409,0.0002457581,0.0004377396,0.001017831],"category_scores_gemma":[0.000427304,0.0003120105,0.0003919977,0.0002456579,0.0003044237,0.0003986932,0.000116936,0.00102727,0.0005380299],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004631584,"about_ca_system_score_gemma":0.0005312043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001640067,"about_ca_topic_score_gemma":0.001402631,"domain_scores_codex":[0.9998302,0.00004885439,0.000005497533,0.00003726918,0.00003514838,0.00004299084],"domain_scores_gemma":[0.999785,0.00004098947,0.00004778755,0.00003115752,0.00003627651,0.0000588945],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.01313477,0.00311683,0.002979159,0.0001731952,0.000141123,0.0003073823,0.0002514283,0.00251112,0.9379059,0.0003522203,0.001847776,0.03727907],"study_design_scores_gemma":[0.001332118,0.1228151,0.03343828,0.00005275465,0.0006540752,0.001925857,0.0002769141,0.01840081,0.7961046,0.0005748144,0.02432419,0.0001004886],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907469,0.002542926,0.003036025,0.0001637611,0.00007324421,0.0001683998,0.0007281211,0.0001833191,0.002357455],"genre_scores_gemma":[0.991416,0.001902534,0.001507576,0.0001307092,0.0000740669,0.0001770288,0.0009384304,0.00008647471,0.003767188],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001640067,"threshold_uncertainty_score":0.003405035,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02094923130325893,"score_gpt":0.3477244181047692,"score_spread":0.3267751868015102,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}