{"id":"W2269478947","doi":"10.1161/hyp.60.suppl_1.a258","title":"Abstract 258: Angiotensin 1-7 Attenuates Endothelin-1-Induced Endothelial Cell Inflammation and Growth Through Nitric Oxide Production and Activation of Mas and EndothelinB Receptors","year":2012,"lang":"en","type":"article","venue":"Hypertension","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Public Health","funders":"","keywords":"Enos; Vasoprotective; Nitric oxide; Angiotensin II; Endothelin 1; Receptor; Endocrinology; Endothelin receptor; Internal medicine; Antagonist; Endothelial stem cell; Receptor antagonist; Chemistry; Proliferating cell nuclear antigen; Cell growth; Pharmacology; Medicine; Nitric oxide synthase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001723685,0.0005548586,0.0006517411,0.000207364,0.0001264771,0.0002898039,0.0003041325,0.0004899022,0.00706711],"category_scores_gemma":[0.0001957066,0.0001657107,0.0002687725,0.0001289765,0.0002482026,0.0003925689,0.0001947227,0.001291926,0.001342513],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000148481,"about_ca_system_score_gemma":0.0003409225,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000351695,"about_ca_topic_score_gemma":0.0003671744,"domain_scores_codex":[0.9998548,0.00002835289,0.00001258819,0.00001521757,0.00004422646,0.0000447667],"domain_scores_gemma":[0.9998723,0.00002058965,0.00002187944,0.0000105301,0.0000250255,0.00004961626],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002922551,0.0005615656,0.0002354267,0.0003667725,0.00003752549,0.0002788792,0.00002679602,0.00007938497,0.9864238,0.0002173687,0.0007752354,0.008074646],"study_design_scores_gemma":[0.000756736,0.006870315,0.01379004,0.00006725779,0.0001398104,0.0007520682,0.00008880459,0.00127859,0.968311,0.0002549085,0.00767657,0.00001392358],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.976497,0.01192887,0.002172834,0.0009808686,0.0009793082,0.00008778649,0.0007913631,0.0002374183,0.006324568],"genre_scores_gemma":[0.9629077,0.00817807,0.003006797,0.0007123402,0.0006326937,0.0001542948,0.00141955,0.00006140936,0.02292719],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00706711,"threshold_uncertainty_score":0.02364182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03272118721144509,"score_gpt":0.2446166117406124,"score_spread":0.2118954245291673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}