{"id":"W2269478947","doi":"10.1161/hyp.60.suppl_1.a258","title":"Abstract 258: Angiotensin 1-7 Attenuates Endothelin-1-Induced Endothelial Cell Inflammation and Growth Through Nitric Oxide Production and Activation of Mas and EndothelinB Receptors","year":2012,"lang":"en","type":"article","venue":"Hypertension","topic":"Renin-Angiotensin System Studies","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Public Health","funders":"","keywords":"Enos; Vasoprotective; Nitric oxide; Angiotensin II; Endothelin 1; Receptor; Endocrinology; Endothelin receptor; Internal medicine; Antagonist; Endothelial stem cell; Receptor antagonist; Chemistry; Proliferating cell nuclear antigen; Cell growth; Pharmacology; Medicine; Nitric oxide synthase; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000451514,0.000317717,0.0006139507,0.0002426542,0.0001673076,0.00002187452,0.00003306473,0.0002035348,0.00000550336],"category_scores_gemma":[0.0007602865,0.0002527591,0.00007006482,0.0002121106,0.0001438718,0.000509745,0.00007105261,0.0001938307,0.00001003639],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004844417,"about_ca_system_score_gemma":0.00002896697,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003003056,"about_ca_topic_score_gemma":0.000003151061,"domain_scores_codex":[0.9982296,0.00009363762,0.0005369125,0.0004344189,0.0003643975,0.0003410967],"domain_scores_gemma":[0.9985727,0.0002267465,0.0003599449,0.0002629651,0.0004464994,0.0001311293],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002456256,0.00007661929,0.07183247,0.0001503068,0.00006951548,0.000003729618,0.000906698,6.748315e-7,0.9232937,0.0000325935,0.0003502057,0.003037859],"study_design_scores_gemma":[0.001042021,0.0001020414,0.329954,0.0003069553,0.0001862465,0.000301837,0.0003263379,0.00003914749,0.6672413,0.0000555722,0.0002565076,0.0001879885],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954739,0.001821894,0.00003564602,0.001212494,0.0002775435,0.0008281769,0.000007701889,0.00007736837,0.0002652638],"genre_scores_gemma":[0.9948652,0.001286321,0.002909834,0.00009592213,0.0006074258,0.00001393729,0.00001742567,0.00005376125,0.0001502019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2581216,"threshold_uncertainty_score":0.9999925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03272118721144509,"score_gpt":0.2446166117406124,"score_spread":0.2118954245291673,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}