{"id":"W2270148235","doi":"10.4049/jimmunol.1502422","title":"Simulated Night Shift Disrupts Circadian Rhythms of Immune Functions in Humans","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Circadian rhythm and melatonin","field":"Neuroscience","cited_by":143,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"Neuroscience Center Zurich, University of Zurich; Canadian Institutes of Health Research; McGill University","keywords":"Circadian rhythm; Rhythm; Immune system; Neuroscience; Biology; Phase response curve; Medicine; Internal medicine; Circadian clock; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005571236,0.000124374,0.0003292196,0.0003105369,0.000102608,0.000006979802,0.0003861699,0.000113796,0.0002836974],"category_scores_gemma":[0.0004852866,0.000068511,0.0001359644,0.000336269,0.0004397891,0.0001997069,0.0000605603,0.0003661354,0.00009325941],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007130163,"about_ca_system_score_gemma":0.0001042595,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003690031,"about_ca_topic_score_gemma":0.00002602453,"domain_scores_codex":[0.9983056,0.0003892738,0.0007142755,0.0001170551,0.000154011,0.0003198438],"domain_scores_gemma":[0.9982881,0.0007403184,0.0005016248,0.0003608318,0.00005876744,0.00005034325],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003048868,0.0001095276,0.002474954,0.000004292888,0.00003480525,0.00008760409,0.001805601,0.0001255113,0.9861987,0.006199294,0.00004385068,0.002610969],"study_design_scores_gemma":[0.004017654,0.000802008,0.4396141,0.0002618372,0.00006502793,0.001410293,0.0003858493,0.0000211447,0.5428278,0.002890403,0.007452716,0.0002511089],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938241,0.001863089,0.0002711773,0.002314829,0.0007920224,0.0001018174,0.000008265338,0.00001029345,0.0008143723],"genre_scores_gemma":[0.9985644,0.0005338338,0.000005458643,0.00009403359,0.00007185754,8.545779e-7,1.909453e-7,0.00001571052,0.00071362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4433709,"threshold_uncertainty_score":0.3106288,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01861183071929052,"score_gpt":0.2526797493120822,"score_spread":0.2340679185927917,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}