{"id":"W2270189214","doi":"10.1016/s1473-3099(16)00013-x","title":"Early HIV treatment to forestall drug resistance","year":2016,"lang":"en","type":"letter","venue":"The Lancet Infectious Diseases","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"","keywords":"Emtricitabine; Lamivudine; Drug resistance; Medicine; Tenofovir; Epidemiology; Drug; Pharmacology; Virology; Internal medicine; Human immunodeficiency virus (HIV); Biology; Virus; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001282281,0.0003457263,0.0005387345,0.0004396742,0.0006982187,0.001787339,0.0005513358,0.001530698,0.02220826],"category_scores_gemma":[0.006467383,0.0001399661,0.0004941871,0.0002433827,0.0003299208,0.001301927,0.0007861085,0.002878924,0.004143506],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006065767,"about_ca_system_score_gemma":0.0008670556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001017698,"about_ca_topic_score_gemma":0.002917257,"domain_scores_codex":[0.9992569,0.0002019894,0.00007196964,0.00008179499,0.0002249462,0.0001623912],"domain_scores_gemma":[0.9971759,0.0009707566,0.0004239527,0.0002093455,0.0005333358,0.0006866333],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004581184,0.0003457627,0.01489772,0.0008440419,0.0001270528,0.001219554,0.0002905132,0.0001372639,0.001522298,0.008957851,0.3348726,0.6363273],"study_design_scores_gemma":[0.0002941603,0.0006185521,0.02159762,0.002617049,0.0001977943,0.005038235,0.0002846899,0.0005807834,0.002038895,0.007194087,0.9594949,0.00004320461],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0444078,0.3225417,0.009834632,0.4188817,0.05583453,0.0003408255,0.001649061,0.00140598,0.1451038],"genre_scores_gemma":[0.4002662,0.1636968,0.006637586,0.2435001,0.104653,0.0002131561,0.002009748,0.0004569052,0.0785666],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02220826,"threshold_uncertainty_score":0.07429409,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.015232422947352,"score_gpt":0.257454673886534,"score_spread":0.242222250939182,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}