{"id":"W2270438568","doi":"10.3389/fcell.2015.00081","title":"The Good and Bad of β-Catenin in Kidney Development and Renal Dysplasia","year":2015,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Renal dysplasia; Kidney development; Kidney; Pathogenesis; Epigenetics; Dysplasia; Kidney disease; Biology; Disease; Medicine; Catenin; Etiology; Pathology; Bioinformatics; Cancer research; Internal medicine; Genetics; Gene; Wnt signaling pathway; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003493817,0.0002868734,0.0006520992,0.0001233755,0.00006281678,0.00001179597,0.0001459701,0.0005076152,0.000001073],"category_scores_gemma":[0.0000231766,0.0001824593,0.00003743636,0.0001190523,0.0003393489,0.000002904191,0.000246597,0.0002205125,0.000001040784],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006164942,"about_ca_system_score_gemma":0.0006175145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001643301,"about_ca_topic_score_gemma":0.00002905448,"domain_scores_codex":[0.998612,0.0001131223,0.0005036304,0.0004336626,0.00005882064,0.0002787654],"domain_scores_gemma":[0.9995883,0.00002042823,0.0001608194,0.00008277499,0.00001823581,0.000129425],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008054847,0.00002523887,0.002794584,0.001140862,0.0001470337,0.00001070509,0.0001769539,1.336617e-7,0.0003899806,0.00001757598,0.003769908,0.9914465],"study_design_scores_gemma":[0.0006055852,0.00009158155,0.00008878892,0.0007650246,0.00002953007,0.00006867796,0.0001488873,0.000001250134,0.001125851,0.000071341,0.9967363,0.0002671492],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006348813,0.9914628,0.00001947656,0.00001676178,0.0002892873,0.0002818261,0.00001969141,0.000002316998,0.001559052],"genre_scores_gemma":[0.0005938977,0.994752,0.003651644,0.0000328369,0.00002341927,0.00004840012,0.0002173743,0.00001576585,0.0006646154],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9929664,"threshold_uncertainty_score":0.7440476,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108357856312143,"score_gpt":0.2448850596392299,"score_spread":0.2340492740080156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}