{"id":"W2270438568","doi":"10.3389/fcell.2015.00081","title":"The Good and Bad of β-Catenin in Kidney Development and Renal Dysplasia","year":2015,"lang":"en","type":"review","venue":"Frontiers in Cell and Developmental Biology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Kidney Foundation of Canada","keywords":"Renal dysplasia; Kidney development; Kidney; Pathogenesis; Epigenetics; Dysplasia; Kidney disease; Biology; Disease; Medicine; Catenin; Etiology; Pathology; Bioinformatics; Cancer research; Internal medicine; Genetics; Gene; Wnt signaling pathway; Embryonic stem cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003112102,0.0005184559,0.0007509724,0.001657727,0.0002425441,0.0007367149,0.0005390836,0.000939008,0.002915682],"category_scores_gemma":[0.0004685453,0.0001650418,0.0002782707,0.001541622,0.0003870198,0.00097554,0.0006346194,0.001216058,0.001591297],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005703084,"about_ca_system_score_gemma":0.0008679003,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006905842,"about_ca_topic_score_gemma":0.001288384,"domain_scores_codex":[0.9998852,0.00001701179,0.0000183807,0.00001935973,0.00004506702,0.00001501298],"domain_scores_gemma":[0.9998586,0.00005156685,0.00002273303,0.000004601406,0.00003851961,0.00002398095],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008012028,0.00003835651,0.000308172,0.01173417,0.00006904238,0.0004562707,0.00008159057,0.0002883993,0.002938597,0.006985301,0.05074067,0.9262794],"study_design_scores_gemma":[0.000006358006,0.0000329432,0.0008188615,0.001638937,0.00005557669,0.002118239,0.00004702225,0.00004217576,0.0004806247,0.002049696,0.9926968,0.0000126769],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001475359,0.9981508,0.0001180755,0.000311066,0.0001993137,0.000002001936,0.00001887909,0.000008294232,0.001044058],"genre_scores_gemma":[0.001059854,0.997631,0.000130363,0.0001751974,0.0001782922,0.000002791845,0.0000323929,0.000001594167,0.0007885033],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002915682,"threshold_uncertainty_score":0.009753942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0108357856312143,"score_gpt":0.2448850596392299,"score_spread":0.2340492740080156,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}