{"id":"W2270489425","doi":"10.13179/canchemtrans.2013.01.03.0027","title":"A New Cytotoxic Carbazole Alkaloid Isolated from the Stem Bark of Malaysian Clausena excavata","year":2013,"lang":"en","type":"article","venue":"Canadian Chemical Transactions","topic":"Plant chemical constituents analysis","field":"Agricultural and Biological Sciences","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Alkaloid; Carbazole; Cytotoxic T cell; Bark (sound); Chemistry; Traditional medicine; Stereochemistry; Organic chemistry; Medicine; Forestry; Geography; Biochemistry; In vitro","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":{"n_in":0,"stratum":"venue_new","weight":2684.24666666667,"opus":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Isolation of a cytotoxic alkaloid from a plant; natural-product chemistry."},"gpt":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"The study isolates and tests plant compounds for cytotoxicity, not research itself."},"grok":{"tier":"OUT","genre":"empirical","about_ca":false,"confidence":"high","reason":"Natural-product chemistry isolation of a cytotoxic alkaloid; domain biomedical chemistry."}},"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00003673996,0.0003356462,0.0002165077,0.0004225389,0.000202902,0.0001609034,0.0001496661,0.0002527876,0.00167532],"category_scores_gemma":[0.00008906011,0.00009166464,0.0001373921,0.0002632218,0.0002193783,0.0002364312,0.0001705437,0.0003647649,0.0002054958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008743477,"about_ca_system_score_gemma":0.000213011,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001144038,"about_ca_topic_score_gemma":0.002227115,"domain_scores_codex":[0.9999784,0.000002341255,0.000002489536,0.000006535039,0.000007029243,0.000003146638],"domain_scores_gemma":[0.9999516,0.00001343219,0.00001098362,0.000004237258,0.00001076664,0.000009072067],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002589131,0.0000800028,0.001441367,0.0004550962,0.00001769274,0.000896786,0.0001094159,0.0001233517,0.9850599,0.00007799571,0.00009994086,0.01137961],"study_design_scores_gemma":[0.0002194536,0.002781367,0.1135149,0.0002357919,0.0002019348,0.00944184,0.0006841137,0.001618105,0.8522115,0.0003033327,0.01872436,0.00006331587],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9863545,0.009023416,0.001270284,0.0001799979,0.00003142342,0.00006716038,0.0005255743,0.00003093294,0.002516776],"genre_scores_gemma":[0.9935266,0.002154522,0.001976349,0.0001463793,0.00001625811,0.00001448771,0.0004930607,0.000005553671,0.001666864],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00167532,"threshold_uncertainty_score":0,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01248617027738525,"score_gpt":0.1696771120360176,"score_spread":0.1571909417586323,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}