{"id":"W2270601398","doi":"10.1093/infdis/jiv760","title":"Inhibition of MicroRNA 195 Prevents Apoptosis and Multiple-Organ Injury in Mouse Models of Sepsis","year":2015,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":75,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; National Natural Science Foundation of China","keywords":"microRNA; Apoptosis; Sepsis; Biology; Cell biology; Cancer research; Medicine; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002653289,0.00008660334,0.000300901,0.0001700656,0.00001791647,0.000004243656,0.00004181938,0.0000360826,0.00001285429],"category_scores_gemma":[0.000101222,0.00005861985,0.00008609895,0.0001407457,0.00005742875,0.000126734,0.00002341681,0.0001028797,2.712487e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006955225,"about_ca_system_score_gemma":0.0001207875,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002167908,"about_ca_topic_score_gemma":0.0000174993,"domain_scores_codex":[0.9991962,0.00007958654,0.0003729578,0.00005447094,0.0002098127,0.00008701347],"domain_scores_gemma":[0.9991381,0.00006524284,0.0003650843,0.00011495,0.0001971555,0.0001194725],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.006437158,0.002280846,0.1267717,0.0003568102,0.0004599546,0.000008423065,0.005017963,0.001829507,0.8483689,0.0001049435,0.0008276499,0.007536149],"study_design_scores_gemma":[0.01253246,0.003600863,0.01108965,0.0009124106,0.0006259251,0.0001247587,0.001221767,0.0006045602,0.9570125,0.01205557,0.00003789496,0.0001816744],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982326,0.0010258,0.0003083357,0.0001110001,0.00006652482,0.0001697853,0.00003556018,0.000005702046,0.00004466341],"genre_scores_gemma":[0.998767,0.0009681016,0.00005323978,0.0001203812,0.00005890151,0.000001437857,0.000001570824,0.00001302767,0.00001639764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1156821,"threshold_uncertainty_score":0.2390448,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01731942892675933,"score_gpt":0.2683091600435717,"score_spread":0.2509897311168124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}