{"id":"W2270819285","doi":"10.1152/ajpheart.00873.2015","title":"Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Juvenile Diabetes Research Foundation United States of America; Heart And Stroke Foundation Of Quebec; Canadian Institutes of Health Research; Regeneron Pharmaceuticals; Government of Canada; Heart and Stroke Foundation of Canada","keywords":"Contractility; Endocrinology; Internal medicine; Vascular smooth muscle; GPER; Biology; Estrogen; Estrogen receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009448577,0.0002171762,0.0001880553,0.0001342834,0.0001877845,0.000223705,0.0001140516,0.0001786186,0.001278499],"category_scores_gemma":[0.0001171098,0.00008400741,0.0001900219,0.0000963294,0.0001635455,0.0001233736,0.0001648721,0.0002335336,0.0001939711],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00014801,"about_ca_system_score_gemma":0.0001963951,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007797636,"about_ca_topic_score_gemma":0.001424864,"domain_scores_codex":[0.9999189,0.00001639127,0.000004665167,0.00001533392,0.0000185074,0.00002625555],"domain_scores_gemma":[0.9999297,0.000007359834,0.00001995279,0.000006047035,0.000006995537,0.00003000507],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001022731,0.00005717769,0.007007629,0.00009758437,0.00003283408,0.0004867082,0.00007233862,0.0001074727,0.9814298,0.0006446954,0.000272273,0.008768714],"study_design_scores_gemma":[0.0001515248,0.0009744818,0.3676648,0.00003904743,0.0002234437,0.001701556,0.0003820222,0.002492904,0.6078171,0.001076,0.01744718,0.00003009411],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862598,0.007049045,0.003072333,0.0003040873,0.00008103193,0.00001167634,0.0004581735,0.00007897793,0.002684822],"genre_scores_gemma":[0.9940645,0.001924424,0.0006587351,0.00007854672,0.00002378916,0.00001094332,0.0002237103,0.00001144507,0.003003957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001278499,"threshold_uncertainty_score":0.004276991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01228438384805562,"score_gpt":0.2243406649618247,"score_spread":0.2120562811137691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}