{"id":"W2270819285","doi":"10.1152/ajpheart.00873.2015","title":"Estrogen and testosterone in concert with EFNB3 regulate vascular smooth muscle cell contractility and blood pressure","year":2016,"lang":"en","type":"article","venue":"American Journal of Physiology-Heart and Circulatory Physiology","topic":"Axon Guidance and Neuronal Signaling","field":"Neuroscience","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Montreal Heart Institute; Centre Hospitalier de l’Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Natural Sciences and Engineering Research Council of Canada; Juvenile Diabetes Research Foundation United States of America; Heart And Stroke Foundation Of Quebec; Canadian Institutes of Health Research; Regeneron Pharmaceuticals; Government of Canada; Heart and Stroke Foundation of Canada","keywords":"Contractility; Endocrinology; Internal medicine; Vascular smooth muscle; GPER; Biology; Estrogen; Estrogen receptor; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002206437,0.0002384436,0.0006843173,0.00008722246,0.0001115436,0.00001131045,0.0001367533,0.00007673231,0.00001832864],"category_scores_gemma":[0.00006336082,0.0001551397,0.00006604459,0.0001292261,0.001652477,0.0002516204,0.00007182037,0.0002841274,0.000001504757],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008842337,"about_ca_system_score_gemma":0.00006891028,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002683069,"about_ca_topic_score_gemma":0.000002122777,"domain_scores_codex":[0.9981081,0.000422283,0.0003715442,0.0005725488,0.0001463767,0.0003791645],"domain_scores_gemma":[0.9986235,0.0004941104,0.0004082133,0.0002354988,0.00005660109,0.0001820229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0002665244,0.00009714583,0.006259976,0.0000258184,0.00003611075,0.000004168453,0.000112997,0.00002132773,0.9920732,0.00005407871,0.000006762848,0.001041914],"study_design_scores_gemma":[0.001903569,0.001452524,0.9305106,0.00006953243,0.0001121407,0.0001342184,0.00008085398,0.00002802837,0.06391051,0.0005420008,0.001046428,0.0002095849],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977881,0.001790811,0.000002434124,0.0001965959,0.00005115695,0.0001381775,0.000007264286,0.00001224122,0.00001317838],"genre_scores_gemma":[0.9985265,0.0005155114,0.00005735663,0.0007763293,0.00009254969,0.000005475084,2.843081e-7,0.00002023053,0.000005807138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9281627,"threshold_uncertainty_score":0.6326414,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01228438384805562,"score_gpt":0.2243406649618247,"score_spread":0.2120562811137691,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}