{"id":"W2270849998","doi":"10.15252/embj.201591293","title":"BRPF3‐HBO1 regulates replication origin activation and histone H3K14 acetylation","year":2015,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":145,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; McGill University Health Centre; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital; Université Laval","funders":"Canadian Institutes of Health Research; Kræftens Bekæmpelse; Novo Nordisk Fonden; Lundbeckfonden; Danmarks Grundforskningsfond; Gentofte Hospital","keywords":"Biology; Acetylation; Histone; Cell biology; Replication (statistics); Biochemistry; DNA; Gene; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002026665,0.0004428521,0.000362793,0.0004185456,0.000534209,0.001084847,0.0006299107,0.000602942,0.004024717],"category_scores_gemma":[0.0003445788,0.0004790047,0.0004293883,0.0003111754,0.0005702067,0.0007949614,0.0009391315,0.00102622,0.001752428],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009320764,"about_ca_system_score_gemma":0.0003366765,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001670101,"about_ca_topic_score_gemma":0.002483851,"domain_scores_codex":[0.9996433,0.00001571697,0.00001382764,0.0001092646,0.00007266852,0.0001452282],"domain_scores_gemma":[0.9997496,0.00002762275,0.00008190816,0.00003524282,0.00002547051,0.00008010567],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004556333,0.00002757326,0.0009211545,0.00003596615,0.000007477649,0.00006015395,0.00001669057,0.00006498179,0.9961287,0.0002760279,0.0002491627,0.001756439],"study_design_scores_gemma":[0.00004332568,0.00007008002,0.03679087,0.000008354187,0.00001453531,0.0002445219,0.00007282021,0.001247218,0.9573563,0.0002684675,0.003869388,0.00001406512],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846445,0.003914605,0.004909103,0.0004419769,0.0001473423,0.00002369596,0.001631132,0.0005271318,0.003760552],"genre_scores_gemma":[0.9937168,0.0004186134,0.0008528187,0.0000737416,0.00001191466,0.00001070876,0.001368273,0.00009671599,0.003450338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004024717,"threshold_uncertainty_score":0.01346403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0256434573528922,"score_gpt":0.294458628941911,"score_spread":0.2688151715890189,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}