{"id":"W2271100450","doi":"10.1038/srep11760","title":"Novel ZnO hollow-nanocarriers containing paclitaxel targeting folate-receptors in a malignant pH-microenvironment for effective monitoring and promoting breast tumor regression","year":2015,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":91,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Indian Institute of Technology Kharagpur; Dalhousie University; Virginia Commonwealth University; Department of Science and Technology, Ministry of Science and Technology, India; Department of Biotechnology, Ministry of Science and Technology, India; Fondation de la recherche en santé du Nouveau-Brunswick; Council of Scientific and Industrial Research, India","keywords":"Nanocarriers; Paclitaxel; In vivo; Chemistry; Cancer research; Folate receptor; Pharmacology; Cancer cell; Targeted therapy; In vitro; Cancer; Medicine; Drug; Biology; Biochemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008973956,0.0002228203,0.0002024087,0.000140435,0.000104784,0.0002165496,0.0002095028,0.0002715551,0.0004314629],"category_scores_gemma":[0.0001465789,0.0001384442,0.0001463618,0.0001070548,0.0001580279,0.000236191,0.0001544946,0.0002204255,0.0001621641],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004796466,"about_ca_system_score_gemma":0.0002001315,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001583943,"about_ca_topic_score_gemma":0.003130369,"domain_scores_codex":[0.9999349,0.000004852092,0.000004172566,0.00002323237,0.00001846061,0.00001434155],"domain_scores_gemma":[0.9999366,0.00001057695,0.00002324614,0.000004180503,0.00001187099,0.00001352178],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004033242,0.000007481188,0.00004106237,0.00002747663,0.000001912794,0.00002998978,0.000009749589,0.0001723367,0.9979268,0.0001204781,0.00003601273,0.001586361],"study_design_scores_gemma":[0.00001778378,0.0000909361,0.0005488584,0.000003031573,0.000008971478,0.00006618153,0.000008630691,0.002200656,0.9953567,0.0000357827,0.001656332,0.000006008569],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9535232,0.003148986,0.03980038,0.0002142201,0.00008689315,0.00009234144,0.00029615,0.0004605063,0.002377366],"genre_scores_gemma":[0.9749703,0.0009230102,0.02137078,0.00006418619,0.00001280931,0.00004425649,0.0001171717,0.00004176416,0.002455697],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001583943,"threshold_uncertainty_score":0.003480136,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01379351961447497,"score_gpt":0.2439826753440316,"score_spread":0.2301891557295566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}