{"id":"W2271128571","doi":"10.3945/jn.115.223990","title":"The Colonic Microbiome and Epithelial Transcriptome Are Altered in Rats Fed a High-Protein Diet Compared with a Normal-Protein Diet","year":2016,"lang":"en","type":"article","venue":"Journal of Nutrition","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":145,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta","funders":"Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Ruminococcus; Biology; Faecalibacterium prausnitzii; Metabolome; Microbiology; Akkermansia; Akkermansia muciniphila; Butyrate; Cecum; Bifidobacterium breve; Transcriptome; Feces; Microbiome; Escherichia coli; Bifidobacterium; Lactobacillus; Gut flora; Biochemistry; Metabolite; Fermentation; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001342873,0.0004018369,0.0006411945,0.0005891187,0.0004536525,0.0005048097,0.0001700643,0.0005027638,0.001915113],"category_scores_gemma":[0.0002080451,0.0003551104,0.000363338,0.0003431146,0.0006808404,0.0004454906,0.0004217359,0.0008355479,0.0002111782],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003711741,"about_ca_system_score_gemma":0.0004389054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002160221,"about_ca_topic_score_gemma":0.003422781,"domain_scores_codex":[0.9997991,0.00002235862,0.00001069899,0.00005253969,0.00003894694,0.00007633108],"domain_scores_gemma":[0.9996767,0.00002402507,0.00006128303,0.00002558997,0.00003284238,0.000179559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007706941,0.0001568208,0.004003109,0.00003683114,0.00003480669,0.0001058764,0.00005719575,0.00003034545,0.9865835,0.00004096591,0.00004508735,0.001198378],"study_design_scores_gemma":[0.0002021309,0.003939257,0.5325088,0.00002199734,0.0002983033,0.0008325413,0.001418213,0.001453559,0.4572394,0.0003346806,0.001694472,0.00005659035],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999218,0.0001470765,0.000213369,0.00005364728,0.00001879583,0.000003979584,0.0001465549,0.000009331172,0.0001891299],"genre_scores_gemma":[0.9967538,0.0002323929,0.0006096499,0.0001015745,0.0000114511,0.00002799977,0.0003994828,0.00002047089,0.001843136],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002160221,"threshold_uncertainty_score":0.006406724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009134265203156314,"score_gpt":0.2303258307505905,"score_spread":0.2211915655474342,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}