{"id":"W2271523423","doi":"10.1002/wsbm.1329","title":"Heart valve regeneration: the need for systems approaches","year":2016,"lang":"en","type":"review","venue":"WIREs Systems Biology and Medicine","topic":"Electrospun Nanofibers in Biomedical Applications","field":"Materials Science","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Regeneration (biology); Heart valve; Tissue engineering; Regenerative medicine; Biomedical engineering; Biochemical engineering; Computer science; Biology; Computational biology; Stem cell; Cell biology; Engineering; Medicine; Cardiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001998062,0.0003673907,0.001622133,0.0001043369,0.0004123255,0.0000359111,0.0004522788,0.0005908106,0.00001742517],"category_scores_gemma":[0.0001325775,0.0001515474,0.0001626732,0.0001904125,0.001174866,0.00003189185,0.00007511865,0.0001565698,0.00005134677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007335853,"about_ca_system_score_gemma":0.0001648746,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008373437,"about_ca_topic_score_gemma":0.000002521989,"domain_scores_codex":[0.9973549,0.0005604986,0.0008846892,0.0006212416,0.0001630205,0.0004157022],"domain_scores_gemma":[0.9971967,0.001468071,0.0005013163,0.0006118388,0.00008573676,0.000136356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003796895,0.0000746254,0.00001245264,0.03650598,0.0006096685,0.000001838612,0.0002503665,0.000001072126,0.00905839,0.4933335,0.2124128,0.2477013],"study_design_scores_gemma":[0.0002465492,0.0001959601,4.287006e-7,0.005969731,0.0003246288,0.0002109962,0.00004315848,0.00002864997,0.00002043807,0.0002920237,0.9924808,0.0001866181],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000003069333,0.9833732,0.007846226,0.002437305,0.00282787,0.002999224,0.0001584566,0.0000806505,0.0002739761],"genre_scores_gemma":[0.0001105321,0.9883562,0.0002169313,0.0001059404,0.004936921,0.003909836,0.0002456177,0.00003492718,0.002083144],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.780068,"threshold_uncertainty_score":0.6179925,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08970296158196651,"score_gpt":0.3536351862622372,"score_spread":0.2639322246802707,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}