{"id":"W2271971696","doi":"10.21037/jgo.2016.01.03","title":"Dose modification and efficacy of nab-paclitaxel plus gemcitabine vs. gemcitabine for patients with metastatic pancreatic cancer: phase III MPACT trial","year":2016,"lang":"en","type":"article","venue":"Journal of Gastrointestinal Oncology","topic":"Pancreatic and Hepatic Oncology Research","field":"Medicine","cited_by":65,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"Celgene","keywords":"Medicine; Gemcitabine; Neutropenia; Pancreatic cancer; Adverse effect; Internal medicine; Paclitaxel; Deoxycytidine; Population; Chemotherapy; Cancer; Nab-paclitaxel; Oncology; Febrile neutropenia; Gastroenterology; Urology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00253822,0.001458623,0.002334648,0.0004122314,0.0003483065,0.001320995,0.001001301,0.001044691,0.003733467],"category_scores_gemma":[0.002294755,0.0004257737,0.002029218,0.0006524532,0.0007909324,0.0008337453,0.0005436474,0.004614401,0.0005571046],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001259926,"about_ca_system_score_gemma":0.002099966,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006464971,"about_ca_topic_score_gemma":0.001562364,"domain_scores_codex":[0.9991985,0.0005184007,0.00004404326,0.00009704717,0.00006251082,0.00007946491],"domain_scores_gemma":[0.9985927,0.0003828726,0.0004185377,0.0001275904,0.00006559962,0.0004126992],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9262391,0.01727161,0.002738234,0.0004150802,0.001352501,0.00007350095,0.00009453346,0.00227431,0.004512981,0.0001375136,0.002094951,0.04279563],"study_design_scores_gemma":[0.7102644,0.2711931,0.01053553,0.00006589891,0.001050581,0.000193878,0.00003300825,0.002294586,0.001677022,0.0003887033,0.002273751,0.00002949273],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914916,0.002506496,0.0003237575,0.0006172253,0.0001685207,0.002023472,0.0007592931,0.00008430165,0.002025323],"genre_scores_gemma":[0.9888164,0.001743824,0.001369018,0.00111746,0.0003092714,0.003118098,0.00163491,0.00004068944,0.001850319],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003733467,"threshold_uncertainty_score":0.01342356,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05354838783683344,"score_gpt":0.398360638520579,"score_spread":0.3448122506837455,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}