{"id":"W2272453669","doi":"10.1016/j.stem.2016.01.009","title":"Compacting Chromatin to Ensure Muscle Satellite Cell Quiescence","year":2016,"lang":"en","type":"letter","venue":"Cell stem cell","topic":"Muscle Physiology and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"Ottawa Hospital; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; MyoD; Chromatin; Cell biology; Satellite; Regulator; Stem cell; Psychological repression; Histone; MyoD Protein; Heterochromatin; Cell; Myocyte; Genetics; Myogenesis; Gene expression; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001786266,0.0006111533,0.0004977637,0.00008518074,0.0001811014,0.00004701283,0.0006979409,0.00122944,0.0001976691],"category_scores_gemma":[0.000007596192,0.000538423,0.000282882,0.0001063279,0.0001171777,0.000005469977,0.0002980986,0.0006822766,0.0009597596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003660106,"about_ca_system_score_gemma":0.0001252088,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003474482,"about_ca_topic_score_gemma":0.000009753143,"domain_scores_codex":[0.9971158,0.0002293907,0.0004423159,0.001080347,0.0002372285,0.0008949478],"domain_scores_gemma":[0.9982536,0.00008431955,0.0003316695,0.001051796,0.0001003036,0.0001783353],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000303338,0.00003490268,0.00006192598,0.000401348,0.00001323504,0.00002157682,0.00008431331,0.00001008002,0.5464085,3.237405e-7,0.4509453,0.001988192],"study_design_scores_gemma":[0.0004212128,0.0002120735,0.0001591699,0.00006407791,0.000027644,0.000001946294,0.00006842872,0.00000198108,0.2885927,0.000009232079,0.7098661,0.0005754781],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5805845,0.01532274,0.001246037,0.06895597,0.003688898,0.002648365,0.0005690099,0.0002632854,0.3267212],"genre_scores_gemma":[0.7071497,0.0008792752,0.0004124424,0.2354842,0.004902848,0.00008093751,0.00102085,0.0002380747,0.04983165],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2768895,"threshold_uncertainty_score":0.9998181,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009710614539270204,"score_gpt":0.2135601132430455,"score_spread":0.2038494987037753,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}