{"id":"W2272494096","doi":"10.1093/annonc/mdu337.10","title":"Prognostic Impact of Change in Neutrophil to Lymphocyte Ratio (Nlr) in Response to Targeted Therapy for Metastatic Renal Cell Carcinoma (Mrcc)","year":2014,"lang":"en","type":"article","venue":"Annals of Oncology","topic":"Inflammatory Biomarkers in Disease Prognosis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"BC Cancer Agency; Sunnybrook Health Science Centre; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Renal cell carcinoma; Neutrophil to lymphocyte ratio; Oncology; Internal medicine; Targeted therapy; Lymphocyte; Immunology; Cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005203625,0.0001882937,0.0004360558,0.0003702292,0.0001978291,0.0005154057,0.0002688532,0.0004267827,0.001052704],"category_scores_gemma":[0.002308566,0.00008344692,0.0003551937,0.0004232767,0.0002296586,0.0004069661,0.0002862943,0.0005431561,0.0002100284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003617028,"about_ca_system_score_gemma":0.0002594725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008510866,"about_ca_topic_score_gemma":0.001505379,"domain_scores_codex":[0.9997042,0.00007971642,0.00003885632,0.00005973548,0.00005920588,0.0000582773],"domain_scores_gemma":[0.9988827,0.0003998951,0.0003585073,0.00004751998,0.0001030826,0.0002082519],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002128513,0.00008606418,0.9855497,0.00002795484,0.0001156963,0.0001217428,0.00003180505,0.0003073415,0.001448339,0.00002649461,0.0001789701,0.009977311],"study_design_scores_gemma":[0.00002759116,0.0008966891,0.9958653,0.000009076647,0.0001406159,0.0004283928,0.00007959251,0.001248767,0.0007138982,0.00007084095,0.0005108332,0.000008406728],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9975044,0.001352901,0.0001140533,0.0001256757,0.00003018979,0.000007443257,0.0002017856,0.000008169691,0.0006553459],"genre_scores_gemma":[0.9994277,0.0001154953,0.00005880702,0.00003336947,0.0000257582,0.000004868069,0.0001873019,0.000001145724,0.0001455099],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001052704,"threshold_uncertainty_score":0.003521681,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1042589687300877,"score_gpt":0.4015745892479451,"score_spread":0.2973156205178574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}