{"id":"W2272616248","doi":"10.1007/978-1-59259-879-3_8","title":"Strategies of Conditional Gene Expression in Myocardium","year":2005,"lang":"en","type":"review","venue":"Methods in molecular medicine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"Providence Health Care; Canadian Institutes of Health Research; St. Paul's Hospital; University of British Columbia","funders":"","keywords":"Transgene; Reporter gene; Gene expression; Transduction (biophysics); Gene; Genetic enhancement; Biology; Green fluorescent protein; Viral vector; Bioluminescence imaging; Computational biology; Expression vector; Cell biology; Molecular biology; Luciferase; Transfection; Genetics; Recombinant DNA; Biophysics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.002740179,0.0004357914,0.001550621,0.0005524256,0.0000187908,0.000007152861,0.0005450096,0.0005664399,0.0001318639],"category_scores_gemma":[0.0003558624,0.0003571396,0.0002897386,0.0004864164,0.0003210563,0.000003919893,0.000184001,0.0005347475,0.000003447139],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007131423,"about_ca_system_score_gemma":0.0005584068,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001341103,"about_ca_topic_score_gemma":0.00002224094,"domain_scores_codex":[0.9951732,0.002357497,0.0009708547,0.0006593475,0.0004398784,0.0003991984],"domain_scores_gemma":[0.9986107,0.0001310448,0.000289487,0.0007795967,0.00009054682,0.00009859884],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001075173,0.00007371427,0.000002037039,0.001401365,0.00008808182,0.0000629236,0.00002381484,0.0001246097,0.5007372,0.00005323704,0.0001533818,0.4971721],"study_design_scores_gemma":[0.001491776,0.001466013,0.00001053846,0.004884571,0.000128981,0.00005310874,0.0001025199,0.00001279411,0.228104,0.0005226097,0.76276,0.0004630248],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009125976,0.9490099,0.04904135,0.00004088756,0.000110308,0.0006123012,0.000028001,0.000005877401,0.001060105],"genre_scores_gemma":[0.00003883242,0.9221786,0.07641061,0.00008026233,0.0002988678,0.0001734935,0.0006716954,0.00007377069,0.00007381687],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7626067,"threshold_uncertainty_score":0.9998881,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07143440106905495,"score_gpt":0.4892580222346398,"score_spread":0.4178236211655848,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}