{"id":"W2272628097","doi":"10.1136/bmj.h5453","title":"Poor quality animal studies cause clinical trials to follow false leads","year":2015,"lang":"en","type":"letter","venue":"BMJ","topic":"Animal testing and alternatives","field":"Veterinary","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Quality (philosophy); Clinical trial; Intensive care medicine; Medicine; Internal medicine","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.141316,0.001421183,0.002679888,0.002016433,0.003698903,0.007920271,0.005327362,0.05415487,0.009075058],"category_scores_gemma":[0.3922446,0.002206457,0.003476051,0.002165649,0.01765179,0.01002207,0.004659033,0.04522526,0.01441675],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007466252,"about_ca_system_score_gemma":0.006181403,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001693004,"about_ca_topic_score_gemma":0.003300597,"domain_scores_codex":[0.812419,0.09989084,0.02147247,0.00942853,0.05370601,0.003083177],"domain_scores_gemma":[0.3820691,0.5058668,0.04039922,0.02626618,0.03395982,0.01143899],"domain_codex":null,"domain_gemma":"methods","domain_candidate":"methods","domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0006152717,0.0001048909,0.002374905,0.001098679,0.0002691889,0.00328392,0.0007643347,0.0001819617,0.000910369,0.02334077,0.9040413,0.06301451],"study_design_scores_gemma":[0.0005890402,0.000449268,0.0022137,0.003326916,0.0001821797,0.005144508,0.0007221222,0.0007343207,0.0007529887,0.07593302,0.9097938,0.0001581907],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0006664397,0.006930904,0.002502636,0.9684795,0.0157579,0.00008364856,0.0001013277,0.0001189571,0.00535879],"genre_scores_gemma":[0.007233547,0.003408802,0.00198511,0.9613494,0.02289602,0.0001594249,0.00005444178,0.00007711865,0.002836167],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.858684,"threshold_uncertainty_score":0.7473593,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.854320461833502,"score_gpt":0.6505099326271196,"score_spread":0.2038105292063823,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}