{"id":"W2272680342","doi":"10.1200/jco.2000.18.24.4038","title":"Phase II Feasibility Study of Sequential Couplets of Cisplatin/Topotecan Followed by Paclitaxel/Cisplatin as Primary Treatment for Advanced Epithelial Ovarian Cancer: A National Cancer Institute of Canada Clinical Trials Group Study","year":2000,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Cancer Agency","funders":"","keywords":"Topotecan; Medicine; Cisplatin; Debulking; Paclitaxel; Ovarian cancer; Oncology; Chemotherapy; Regimen; Internal medicine; Surgery; Cancer; Urology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003038891,0.001840016,0.002753005,0.0005977332,0.0006607884,0.001213435,0.001545207,0.001863214,0.003801441],"category_scores_gemma":[0.001547705,0.0008849422,0.001572538,0.0008362333,0.001708471,0.0007175383,0.0003996047,0.003473312,0.0008151453],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002255531,"about_ca_system_score_gemma":0.005424486,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0075841,"about_ca_topic_score_gemma":0.01473838,"domain_scores_codex":[0.9990336,0.0004992759,0.00003928613,0.000140897,0.0001353364,0.0001517116],"domain_scores_gemma":[0.9983178,0.0002157199,0.0003311703,0.0001542116,0.0001136734,0.0008673911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8347682,0.07847562,0.008880074,0.0005520393,0.001650369,0.0003511516,0.0002568164,0.002817397,0.02270736,0.0001626816,0.002271745,0.04710645],"study_design_scores_gemma":[0.5728184,0.4146939,0.008533522,0.00001872873,0.0003467466,0.0001836952,0.00004109354,0.0007242272,0.001369863,0.000089963,0.001160507,0.00001943506],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912444,0.001236168,0.0004511731,0.0003717302,0.00007718838,0.005087506,0.0005815164,0.00005229202,0.0008981159],"genre_scores_gemma":[0.9854659,0.001890709,0.002510946,0.0007979932,0.0001889554,0.006075078,0.001638621,0.00002349735,0.001408431],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0075841,"threshold_uncertainty_score":0.01636511,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2597301339149043,"score_gpt":0.5603606752653596,"score_spread":0.3006305413504553,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}