{"id":"W2272990307","doi":"","title":"Novel Polysaccharide Based Polymers and Nanoparticles for Controlled Drug Delivery and Biomedical Imaging","year":2012,"lang":"en","type":"dissertation","venue":"TSpace","topic":"Hydrogels: synthesis, properties, applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; University of Toronto","keywords":"Doxorubicin; Drug delivery; Biocompatibility; Biodistribution; In vivo; Nanoparticle; Materials science; Nanotechnology; Biomedical engineering; Chemistry; Pharmacology; Biophysics; In vitro; Medicine; Biochemistry; Chemotherapy; Organic chemistry; Biotechnology; Surgery; Biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002100086,0.0002207518,0.0002778173,0.00007022289,0.0001306995,0.0000366091,0.0001054671,0.0001589122,0.00002129412],"category_scores_gemma":[0.0001093127,0.0002005408,0.00008055938,0.00004142426,0.0001100487,0.000004708207,0.00003013127,0.00007084703,0.000002313656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001289057,"about_ca_system_score_gemma":0.000134657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003474816,"about_ca_topic_score_gemma":0.0001527016,"domain_scores_codex":[0.9989837,0.00002731172,0.0002089998,0.000368582,0.0001089224,0.0003024354],"domain_scores_gemma":[0.9993606,0.00005249161,0.0001354859,0.0002223551,0.00006173387,0.0001673381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004282823,0.00006093076,0.0001188932,0.00006750521,0.00007352004,1.976629e-7,0.0002975465,2.905445e-7,0.9923614,0.00001333661,0.0002853934,0.006292736],"study_design_scores_gemma":[0.002984344,0.00004408279,0.0009673953,0.00005477287,0.0002968508,0.000006869149,0.001539934,0.0007316878,0.9820671,0.0000102178,0.01091321,0.0003834985],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859396,0.01177854,0.0005982742,0.0007892823,0.00009635354,0.0005982634,0.00004492892,0.00002031641,0.0001344354],"genre_scores_gemma":[0.994971,0.0001467572,0.001200417,0.0002174776,0.0001606932,0.0003742665,0.0003923279,0.00005303824,0.002484057],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01163178,"threshold_uncertainty_score":0.8177816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01165335381485492,"score_gpt":0.2739087440390439,"score_spread":0.2622553902241889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}