{"id":"W2273649647","doi":"10.1126/science.aad6778","title":"Editing policy to fit the genome?","year":2016,"lang":"en","type":"article","venue":"Science","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University and Génome Québec Innovation Centre; McGill Genome Centre","funders":"Canada Research Chairs","keywords":"Genome; Computational biology; Genome editing; Biology; Computer science; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.08493277,0.001349433,0.002290769,0.002742787,0.005822631,0.02249033,0.004608097,0.03088526,0.01048842],"category_scores_gemma":[0.1995509,0.001154582,0.001359238,0.001505509,0.02289486,0.0298931,0.0118838,0.02894521,0.0016531],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01185685,"about_ca_system_score_gemma":0.01896171,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004762363,"about_ca_topic_score_gemma":0.004108778,"domain_scores_codex":[0.9167641,0.04312269,0.003948938,0.008239675,0.01676742,0.01115714],"domain_scores_gemma":[0.8484058,0.1096012,0.008210798,0.0112429,0.01312152,0.00941782],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.00004657169,0.00006618226,0.001014059,0.00007702247,0.00004610117,0.0001358217,0.001687707,0.001617362,0.0006870216,0.9788496,0.007595457,0.008177053],"study_design_scores_gemma":[0.00002448657,0.00003630361,0.0004205503,0.0001721376,0.00001775566,0.00006132894,0.00112604,0.001085201,0.0004259026,0.9755078,0.02105833,0.00006432909],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":"theoretical_or_conceptual","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.05412631,0.002798765,0.11774,0.6258499,0.003108525,0.0003240648,0.0002158877,0.0005443566,0.1952923],"genre_scores_gemma":[0.8518315,0.0007399248,0.02759596,0.1088658,0.001707905,0.0007366497,0.00007611555,0.0003820429,0.008064162],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08493277,"threshold_uncertainty_score":0.4491728,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008400296248479405,"score_gpt":0.3200319843865446,"score_spread":0.3116316881380652,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}