{"id":"W2273774884","doi":"10.1128/msphere.00014-15","title":"The Human Adenovirus Type 5 E4orf6/E1B55K E3 Ubiquitin Ligase Complex Can Mimic E1A Effects on E2F","year":2015,"lang":"en","type":"article","venue":"mSphere","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; McGill University","funders":"Else Kröner-Fresenius-Stiftung; Deutsche Forschungsgemeinschaft; Ministère du Développement Économique, de l’Innovation et de l’Exportation; Wilhelm Sander-Stiftung; Bar-Ilan University; Government of Canada; McGill University","keywords":"Ubiquitin ligase; Ubiquitin; Chemistry; Cell biology; Molecular biology; Biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003713024,0.0002342031,0.0001728136,0.00002285419,0.000291878,0.00007748898,0.0005394187,0.0001578963,0.00009942946],"category_scores_gemma":[0.0001270406,0.0001798084,0.00008694315,0.0001459196,0.0001459418,0.000002312315,0.0001606446,0.0002288907,0.0002679834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006401524,"about_ca_system_score_gemma":0.0002374494,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001106576,"about_ca_topic_score_gemma":0.002123066,"domain_scores_codex":[0.9983059,0.0002680928,0.0001875359,0.0003995102,0.0003283963,0.0005106243],"domain_scores_gemma":[0.9986936,0.00004342153,0.00006792032,0.0007904415,0.0001576972,0.0002468979],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001326559,0.00009522289,0.0007033075,0.00002660254,0.00009723155,0.00002693821,0.0000674645,0.00006468198,0.9122666,0.0001566646,0.07028547,0.01488332],"study_design_scores_gemma":[0.001524159,0.006014041,0.001116342,0.00002916262,0.00001691794,0.00001100088,0.0001190548,0.00003108145,0.8331947,0.0003320191,0.1572903,0.0003212567],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991429,0.001844748,0.000003968025,0.0009672516,0.0002127661,0.0002897797,0.0000197343,0.00003416727,0.005198631],"genre_scores_gemma":[0.9925633,0.00009052846,0.00004824539,0.001327833,0.0006148648,0.00004253514,0.0001324872,0.00006252473,0.005117667],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08700481,"threshold_uncertainty_score":0.7332373,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0437946836434685,"score_gpt":0.329248429925122,"score_spread":0.2854537462816535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}