{"id":"W2274228022","doi":"10.4049/jimmunol.182.supp.133.16","title":"Surfactant Protein D is cleaved by matrix metalloprotease-9, resulting in disruption of collectin function (133.16)","year":2009,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Neonatal Respiratory Health Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Immunovaccine (Canada)","funders":"","keywords":"Proteases; Collectin; Surfactant protein D; Matrix metalloproteinase; Metalloproteinase; Protease; Innate immune system; Surfactant protein A; Biology; Serine protease; Chemotaxis; Microbiology; Biochemistry; Chemistry; Pulmonary surfactant; Enzyme; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002366328,0.0004385779,0.0002293015,0.0002353743,0.0001499415,0.0002263446,0.000137125,0.0003187477,0.001470508],"category_scores_gemma":[0.0001935495,0.0001479914,0.0004856085,0.0001386624,0.0001995688,0.0001208033,0.0002253704,0.0003641218,0.0005260389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002856887,"about_ca_system_score_gemma":0.0002018377,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000684869,"about_ca_topic_score_gemma":0.0005248107,"domain_scores_codex":[0.999797,0.00003656538,0.00002883207,0.00003467538,0.00004785567,0.00005495053],"domain_scores_gemma":[0.9998665,0.00001826718,0.00005372605,0.00001277463,0.00001485236,0.00003377902],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005877424,0.00001054225,0.0002545,0.00001722597,0.000005587219,0.00009793581,0.000003862849,0.00001078233,0.9990116,0.00003233241,0.00002455155,0.0004720963],"study_design_scores_gemma":[0.00001426551,0.0002081941,0.006397317,0.000004966947,0.00001225873,0.0007292919,0.0000189482,0.0003703542,0.9905922,0.00005250709,0.00159656,0.000003072159],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912975,0.001214089,0.005580404,0.000131959,0.00004527604,0.00004733865,0.0006035027,0.00008485454,0.0009951115],"genre_scores_gemma":[0.994785,0.0006123688,0.002420011,0.00007809899,0.000008386851,0.0000255535,0.0006468829,0.0000136852,0.001409954],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001470508,"threshold_uncertainty_score":0.00491935,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03043325495875614,"score_gpt":0.3515312903353354,"score_spread":0.3210980353765792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}