{"id":"W2274835781","doi":"10.2337/db15-1334","title":"Sorcin Links Pancreatic β-Cell Lipotoxicity to ER Ca2+ Stores","year":2016,"lang":"en","type":"article","venue":"Diabetes","topic":"Pancreatic function and diabetes","field":"Medicine","cited_by":70,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Heart, Lung, and Blood Institute; Biotechnology and Biological Sciences Research Council; National Institutes of Health; European Foundation for the Study of Diabetes; Diabetes UK; Wellcome Trust; Medical Research Council; Wellcome","keywords":"Lipotoxicity; Internal medicine; Endocrinology; Cell biology; Biology; Medicine; Diabetes mellitus; Insulin resistance","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003077005,0.0009172785,0.0006612836,0.0004703052,0.000190614,0.0008031161,0.0004654974,0.0006554726,0.002602316],"category_scores_gemma":[0.0002673869,0.0002702969,0.0003833009,0.0003169813,0.0005715943,0.0005862126,0.000737625,0.001359448,0.0005040505],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003304418,"about_ca_system_score_gemma":0.000248437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002318827,"about_ca_topic_score_gemma":0.0002689086,"domain_scores_codex":[0.9998444,0.00002801576,0.0000120597,0.00004942729,0.00003676797,0.00002938183],"domain_scores_gemma":[0.999693,0.0000269326,0.0001402757,0.00002770572,0.00003665787,0.00007540394],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003762381,0.0001528295,0.002949321,0.0006151582,0.0001013069,0.0007659166,0.0000441423,0.0002204145,0.9790457,0.0004536846,0.0005326185,0.01135641],"study_design_scores_gemma":[0.0006921305,0.002707845,0.1411899,0.0001694016,0.000395843,0.004230558,0.0003336351,0.002892984,0.8245512,0.003631197,0.01913003,0.00007529133],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9492121,0.03403704,0.009997758,0.001820393,0.0003779356,0.00008899477,0.0008252077,0.0004551705,0.00318542],"genre_scores_gemma":[0.9749781,0.01892577,0.001636013,0.0005563546,0.000160599,0.00005878117,0.0009245937,0.00004783891,0.00271187],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002602316,"threshold_uncertainty_score":0.008705616,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01293461504209448,"score_gpt":0.2373119585251459,"score_spread":0.2243773434830514,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}