{"id":"W2274971138","doi":"10.1021/acs.est.5b04939","title":"Sunlight Irradiation of Highly Brominated Polyphenyl Ethers Generates Polybenzofuran Products That Alter Dioxin-responsive mRNA Expression in Chicken Hepatocytes","year":2016,"lang":"en","type":"article","venue":"Environmental Science & Technology","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Ontario Genomics; University of Ottawa; Carleton University; Environment and Climate Change Canada","funders":"Environment Canada; State Administration of Foreign Experts Affairs; Chinese Academy of Sciences; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Dibenzofuran; Chemistry; Decabromodiphenyl ether; Diphenyl ether; Tetrahydrofuran; Ether; Solvent; Brominated flame retardant; Degradation (telecommunications); Gene expression; Nuclear chemistry; Messenger RNA; Organic chemistry; Fire retardant; Biochemistry; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000751858,0.0002275001,0.0001195767,0.00009616584,0.0000837105,0.0001556892,0.00006834527,0.0001495736,0.0004173393],"category_scores_gemma":[0.00005888758,0.000116429,0.0002061921,0.00006607331,0.0001584382,0.0001017024,0.00007457627,0.0001768547,0.000149199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001684271,"about_ca_system_score_gemma":0.0000875277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009723355,"about_ca_topic_score_gemma":0.001969555,"domain_scores_codex":[0.9999297,0.00001035661,0.000005272492,0.00002263286,0.00001717298,0.00001489779],"domain_scores_gemma":[0.9999477,0.00001501297,0.0000146368,0.000005749336,0.000009212646,0.000007738156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003550561,0.000004192769,0.0001879284,0.0000087238,0.000001655449,0.00001259269,0.000006809139,0.00001527151,0.9995209,0.000005485031,0.000002913372,0.0001979795],"study_design_scores_gemma":[0.000003084923,0.0002059469,0.007761578,0.000001427674,0.000008426284,0.00005479683,0.00003178307,0.0001638092,0.9914367,0.000006732644,0.0003238563,0.000001956201],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980223,0.0004599434,0.0008980653,0.00001917912,0.00000843884,0.000007806356,0.0001269003,0.00001103566,0.0004463148],"genre_scores_gemma":[0.9955623,0.0006487555,0.00164363,0.00003551659,0.000005582347,0.00001833389,0.0003635245,0.000009967719,0.001712446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009723355,"threshold_uncertainty_score":0.001933336,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006876394065830085,"score_gpt":0.2127936786456924,"score_spread":0.2059172845798623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}