{"id":"W2275242090","doi":"10.4049/jimmunol.1501642","title":"Clinical Isolates of <i>Pseudomonas aeruginosa</i> from Chronically Infected Cystic Fibrosis Patients Fail To Activate the Inflammasome during Both Stable Infection and Pulmonary Exacerbation","year":2016,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":44,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital; Carleton University; University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Pseudomonas aeruginosa; Exacerbation; Pyroptosis; Cystic fibrosis; Pathogen; Microbiology; Immunology; Immune system; Secretion; Biology; Medicine; Inflammation; Bacteria; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002873191,0.0003081714,0.0005921904,0.0001473734,0.0003556937,0.0005972204,0.0001799233,0.0004906328,0.0008940962],"category_scores_gemma":[0.0009026011,0.0001814963,0.0003632061,0.0002022796,0.0003217664,0.0003174613,0.0003245033,0.0006930601,0.0002746246],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002578844,"about_ca_system_score_gemma":0.0003230846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001739107,"about_ca_topic_score_gemma":0.001356373,"domain_scores_codex":[0.9995567,0.00005647522,0.00006287481,0.0001186899,0.00008721762,0.0001179102],"domain_scores_gemma":[0.9994534,0.0001110001,0.0001401383,0.00006243274,0.00009523089,0.0001379307],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001284412,0.000282039,0.05209251,0.00007618099,0.0000404927,0.001180428,0.0004405019,0.0001221738,0.9378936,0.0000916445,0.000396193,0.006099838],"study_design_scores_gemma":[0.0001808914,0.008128363,0.7501179,0.00007019579,0.0001625199,0.01338914,0.001449814,0.00134717,0.2213571,0.0001557237,0.003594271,0.00004694932],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9992383,0.0002231381,0.0001843063,0.00006147743,0.000009354938,0.0000201265,0.00006670289,0.000007890942,0.0001886326],"genre_scores_gemma":[0.9988796,0.0001078599,0.0003478436,0.0001123754,0.00001488549,0.00002866284,0.0002779798,0.000006963383,0.000223702],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001739107,"threshold_uncertainty_score":0.003457904,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005202659977322853,"score_gpt":0.2222880677703254,"score_spread":0.2170854077930026,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}