{"id":"W2275803282","doi":"10.1017/s1431927602100006","title":"Transmembrane Signalling of the Insulin Receptor: 3D Reconstruction from STEM Imaging, Crystallography and NMR Spectroscopy.","year":2002,"lang":"en","type":"article","venue":"Microscopy and Microanalysis","topic":"Metabolism, Diabetes, and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Ontario Institute for Cancer Research","funders":"","keywords":"Nuclear magnetic resonance spectroscopy; Crystallography; Insulin receptor; Transmembrane protein; Materials science; Chemistry; Biophysics; Insulin; Receptor; Stereochemistry; Biochemistry; Biology; Internal medicine; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001326562,0.0001979139,0.000307463,0.00007860981,0.0001432827,0.00004613015,0.0001486802,0.0001114933,0.0001893848],"category_scores_gemma":[0.000006188063,0.0001605724,0.0001866807,0.0002093561,0.0002430945,0.0000103377,0.00004641845,0.0001133072,0.000001340957],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007804063,"about_ca_system_score_gemma":0.00001471656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001172504,"about_ca_topic_score_gemma":0.00007544058,"domain_scores_codex":[0.99885,0.00009629832,0.0003129008,0.0004368583,0.00008951544,0.0002144463],"domain_scores_gemma":[0.9994157,0.00001272111,0.0001649741,0.0002847876,0.00005647674,0.00006535339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003231149,0.00002968921,0.006335551,0.00002658496,0.0002200764,1.777204e-7,0.0001837773,0.000006482789,0.9393984,0.00000209619,0.000315504,0.05344931],"study_design_scores_gemma":[0.000594023,0.00003313929,0.0004560835,0.00004214522,0.0003365245,0.000005161919,0.0001750263,0.0001452836,0.9597891,0.00003593412,0.03818884,0.0001987412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7115646,0.2873064,0.0007172459,0.00003391985,0.00009006126,0.0000831185,0.0001048525,0.000005722535,0.00009409947],"genre_scores_gemma":[0.8805115,0.1168849,0.002083608,0.0002105272,0.000121981,0.00000764982,0.00003538162,0.00001988606,0.0001246168],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1704215,"threshold_uncertainty_score":0.6547953,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005579086294845347,"score_gpt":0.2010950171736044,"score_spread":0.195515930878759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}