{"id":"W2275948361","doi":"10.1200/jco.2006.24.18_suppl.14557","title":"A dose and schedule optimizing evaluation of MG98 given as either a 2 hour IV infusion twice weekly or as a 7 day continuous infusion in combination with interferon alpha (INF) in nephrectomized patients (pts) with advanced renal cell carcinoma (RCC)","year":2006,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Renal and related cancers","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Juravinski Cancer Centre","funders":"","keywords":"Medicine; Chills; Nausea; Tolerability; Vomiting; Adverse effect; Regimen; Gastroenterology; Internal medicine; Pharmacokinetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[{"model":"gemma","categories":[],"domain":null,"study_design":"nonrandomized_trial","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"},{"model":"gpt","categories":[],"domain":null,"study_design":"design_other","genre":"empirical","about_ca_system":false,"about_ca_topic":false,"confidence":"low","status":"direct model label, unvalidated"}],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007081109,0.0006684641,0.000916061,0.0003658569,0.000219189,0.0005075969,0.0006176634,0.0006688505,0.001866352],"category_scores_gemma":[0.0008562987,0.0003070476,0.0006461993,0.0004031494,0.0004457142,0.0003537125,0.0002138372,0.001385872,0.0003379943],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005308097,"about_ca_system_score_gemma":0.0007252061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007946179,"about_ca_topic_score_gemma":0.001649091,"domain_scores_codex":[0.9997056,0.0001487175,0.00001915074,0.00005075526,0.00003133867,0.00004436699],"domain_scores_gemma":[0.999671,0.00006814523,0.00008510335,0.00003038815,0.00002074474,0.0001246444],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5226665,0.04835356,0.008402893,0.0007808369,0.0005989437,0.0004148758,0.0004210187,0.005116946,0.1160872,0.0003446914,0.001764656,0.295048],"study_design_scores_gemma":[0.09347733,0.8744876,0.0181133,0.00004199876,0.0002680736,0.0003377791,0.00005596633,0.001586658,0.009143593,0.00007757169,0.002384589,0.00002552266],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953651,0.001478923,0.0006432583,0.00012885,0.00005375683,0.0009106554,0.0001548239,0.00004789962,0.00121668],"genre_scores_gemma":[0.9959996,0.000706924,0.001579301,0.0001049919,0.00006778789,0.0005942367,0.0002707242,0.00001106425,0.0006655132],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001866352,"threshold_uncertainty_score":0.006243527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02023000518055343,"score_gpt":0.3370273800073786,"score_spread":0.3167973748268251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}